| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 8880 |
Name | FUBP1 |
Synonymous | far upstream element (FUSE) binding protein 1;FUBP1;far upstream element (FUSE) binding protein 1 |
Definition | DNA helicase V|far upstream element-binding protein 1 |
Position | 1p31.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | FBP(h) --/ BRCA1(h) (DNA binding; transrepression). | Ku70(h) + Ccte(h) + Pds5A(h) + PPIL1(h) + eIF-3gamma(h) + SAFB1(h) + Wapl(h) + Rad21(h) + SMC-3(h) + SMC1(h) + CAPER-alpha(h) + CNOT3(h) + NCoA-5(h) + SIAHBP1(h) + FBP(h) + HYPA(h) + SKIP(h) + SRm300(h) + SRm160(h) + p54nrb/NonO(h) + rbm25(h) + rbm8A(h) + Pinin(h) + Prp19(h) + cdc5L(h) + Snrp116(h) + Prpf8(h) + Sf3b-4(h) + Sf3b-2(h) + hnRNPM(h) + hnRNP-G(h) <==> Ku70(h):Ccte(h):Pds5A(h):PPIL1(h):eIF-3gamma(h):SAFB1(h):Wapl(h):Rad21(h):SMC-3(h):SMC1(h):CAPER-alpha(h):CNOT3(h):NCoA-5(h):SIAHBP1(h):FBP(h):HYPA(h):SKIP(h):SRm300(h):SRm160(h):p54nrb/NonO(h):rbm25(h):rbm8A(h):Pinin(h):Prp19(h):cdc5L(h):Snrp116(h):Prpf8(h):Sf3b-4(h):Sf3b-2(h):hnRNPM(h):hnRNP-G(h) (binding) | gamma-synuclein(h) + FBP(h) <==> gamma-synuclein(h):FBP(h) (binding) | FBP(h) --> c-myc(h) (DNA binding). | FBP(h) + Grg-1(h) <==> FBP(h):Grg-1(h) (binding) | FBP(h) + Mi2-alpha(h) <==> FBP(h):Mi2-alpha(h) (binding) | FBP(h) + vimentin(h) <==> FBP(h):vimentin(h) (binding) | FBP(h) + CRMP1(h) <==> FBP(h):CRMP1(h) (binding) | FUBP1(h) --> FBP(h) (expression). | FBP-Isoform 1(h) --> c-myc(h) (DNA binding; transregulation). | FBP-Isoform 1(h) + parkin(h) <==> FBP-Isoform 1(h):parkin(h) (binding) | FBP-Isoform 1(h) + ubiquitin(h) --parkin(h)--> FBP-Isoform 1(h){ub} (ubiquitination) | FBP-Isoform 1(h) --> protein remnants (degradation) | FUBP1(h) --> FBP-Isoform 1(h) (expression). | FUBP1(h) --> FBP-Isoform 2(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 58 | Phosphotyrosine. | Swiss-Prot 53.0 | 153 | Phosphothreonine. | Swiss-Prot 53.0 | 630 | Phosphoserine. | Swiss-Prot 53.0 | 153 | Phosphothreonine | 15302935 | Phospho.ELM 6.0 | 630 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 58 | Phosphotyrosine | 15592455 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr1 |
Promoter: 78216865 - 78218865 | Agilent_014791 |
chr1 |
Promoter: 78216865 - 78218865 | GSE27584 |
chr1 |
Promoter: 78216865 - 78218865 | Agilent_014791_44K |