Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

8829

Name

NRP1

Synonymous

neuropilin 1;NRP1;neuropilin 1

Definition

neuropilin-1|transmembrane receptor|vascular endothelial cell growth factor 165 receptor

Position

10p12

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

VEGF-165(h) + NP-1(h) <==> VEGF-165(h):NP-1(h) (binding)
NP-1(h) + PlGF(m) <==> NP-1(h):PlGF(m) (binding)
NP-1(h) + heparin <==> NP-1(h):heparin (binding)
NP-1(h) + (VEGF-165(h))2 <==> NP-1(h):(VEGF-165(h))2 (binding)
NRP1(h) --> NP-1(h) (expression).
NRP1(h) --> NP-1(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

150N-linked (GlcNAc...).Swiss-Prot 53.0
261N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
300N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
522N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
612O-linked (Xyl...) (chondroitin sulfate);alternate.Swiss-Prot 53.0
612O-linked (Xyl...) (heparan sulfate);alternate.Swiss-Prot 53.0
842N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr10

Promoter: 33663076 - 33665076Agilent_014791

chr10

Promoter: 33662956 - 33664956Agilent_014791

chr10

Promoter: 33663339 - 33665339Agilent_014791

chr10

Promoter: 33663076 - 33665076GSE27584

chr10

Promoter: 33662956 - 33664956GSE27584

chr10

Promoter: 33663339 - 33665339GSE27584