| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 81 |
Name | ACTN4 |
Synonymous | actinin, alpha 4;ACTN4;actinin, alpha 4 |
Definition | F-actin cross-linking protein|actinin alpha4 isoform|alpha-actinin-4|focal segmental glomerulosclerosis 1|non-muscle alpha-actinin 4 |
Position | 19q13 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | alpha-actinin-4(h) --> SVIL(h) (binding) | alpha-actinin-4(h) --> Hsc70(h) (binding) | alpha-actinin-4(h) --> Hsp70-1(h) (binding) | alpha-actinin-4(h) + elfin(h) <==> alpha-actinin-4(h):elfin(h) (binding) | alpha-actinin-4(h) + calsarcin-1(h) <==> alpha-actinin-4(h):calsarcin-1(h) (binding) | alpha-actinin-4(h) + calsarcin-2(h) <==> alpha-actinin-4(h):calsarcin-2(h) (binding) | ACTN4(h) --> alpha-actinin-4(h) (expression). | P2RX7(r) --> alpha-actinin-4(h) (binding) | LAMA3(h) --> alpha-actinin-4(h) (binding) | mGluR1b(r) + alpha-actinin-4(h) <==> mGluR1b(r):alpha-actinin-4(h) (binding) | 2 mGluR1b(r) + alpha-actinin-4(h) <==> (mGluR1b(r))2:alpha-actinin-4(h) (binding) | mGluR1a(r) + alpha-actinin-4(h) <==> mGluR1a(r):alpha-actinin-4(h) (binding) | ACTN4(h) --> alpha-actinin-4(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 265 | Phosphotyrosine. | Swiss-Prot 53.0 | 159 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr19 |
Promoter: 43828667 - 43830667 | Agilent_014791 |
chr19 |
Promoter: 43828667 - 43830667 | GSE27584 |
chr19 |
Promoter: 43828667 - 43830667 | Agilent_014791_44K |