Entrez Gene

Basic Information
Gene ID	8038
Name	ADAM12
Synonymous	ADAM metallopeptidase domain 12;ADAM12;ADAM metallopeptidase domain 12
Definition	disintegrin and metalloproteinase domain-containing protein 12\|meltrin-alpha\|metalloprotease-disintegrin 12 transmembrane
Position	10q26
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
ADAM12(h) --> ADAM12-isoform1(h) (expression).
Eve-1c(h) + ADAM12(h) <==> Eve-1c(h):ADAM12(h) (binding)
Eve-1d(h) + ADAM12(h) <==> Eve-1d(h):ADAM12(h) (binding)
ADAM12(h) --> ADAM12(h) (expression).
Abeta40(h) --/ ADAM12(h) (decrease of abundance)
IGFBP-3(h) + ADAM12-isoform2(h) <==> IGFBP-3(h):ADAM12-isoform2(h) (binding)
ADAM12(h) --> ADAM12-isoform2(h) (expression).
IGFBP-3(h) --ADAM12-isoform2(h)--> IGFBP3-p20(h) + protein remnants (cleavage)
IGFBP-3(h) --ADAM12-isoform2(h)--> IGFBP3-p10(h) + protein remnants (cleavage)

Location (AA)	PTM type	Database
Post Translational Modification [Top]
111	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
149	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
381	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
452	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
651	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
907	Phosphotyrosine (by SRC) (By similarity).	Swiss-Prot 53.0

Transcription Factors [Top]