| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7133 |
Name | TNFRSF1B |
Synonymous | tumor necrosis factor receptor superfamily, member 1B;TNFRSF1B;tumor necrosis factor receptor superfamily, member 1B |
Definition | TNF-R2|TNF-RII|p75 TNF receptor|p80 TNF-alpha receptor|soluble TNFR1B variant 1|tumor necrosis factor beta receptor|tumor necrosis factor binding protein 2|tumor necrosis factor receptor 2|tumor necrosis factor receptor superfamily member 1B|tumor necrosi |
Position | 1p36.22 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | TNF-alpha(h){sol} + TNFR2(h) <==> TNF-alpha(h){sol}:TNFR2(h) (binding) | TNFR2(h) + TRAF2(m) <==> TNFR2(h):TRAF2(m) (binding) | TNFR2(h) + TRAF1(m) <==> TNFR2(h):TRAF1(m) (binding) | TNFR2(h) + TRAF2(m) + TRIP(m) <==> TNFR2(h):TRAF2(m):TRIP(m) (binding) | TNFR2(h) + ATP --> TNFR2(h){p} + ADP (phosphorylation) | TNFRSF1B(h) --> TNFR2(h) (expression). | TNFR2(h) --/ GluR2(h) (inhibition; decrease of binding) | TNFR2(h) --/ GluR3(h) (inhibition; decrease of binding) | TNFR2(h) --/ GluR6(h) (inhibition; decrease of abundance) | TNFR2(h) --/ NR2B(h) (inhibition; decrease of abundance) | TNFRSF1B(h) --> TNFR2(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 171 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 193 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 436 | Phosphothreonine | 9535738 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr1 |
Promoter: 12148147 - 12150147 | Agilent_014791 |
chr1 |
Promoter: 12148147 - 12150147 | GoldenGate_Methylation_Cancer_Panel_I |
chr1 |
Promoter: 12148147 - 12150147 | GSE27584 |
chr1 |
Promoter: 12148147 - 12150147 | Agilent_014791_44K |