| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7043 |
Name | TGFB3 |
Synonymous | transforming growth factor, beta 3;TGFB3;transforming growth factor, beta 3 |
Definition | TGF-beta-3|prepro-transforming growth factor beta-3|transforming growth factor beta-3 |
Position | 14q24 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | TGFbeta3(h) + TGFbetaR-II(h) + TGFbetaR-I(mv) <==> TGFbeta3(h):TGFbetaR-II(h):TGFbetaR-I(mv) (binding) | TGFbeta3(h) + TGFbetaR-II(h) <==> TGFbeta3(h):TGFbetaR-II(h) (binding) | LAP1(h) + TGFbeta3(h) <==> LAP1(h):TGFbeta3(h) (binding) | TGFbeta3(h) + TGFbetaR-III(h) <==> TGFbeta3(h):TGFbetaR-III(h) (binding) | TGF-beta3(h) --> TGFbeta3(h) (expression). | TGFbeta3(h) --> Smad2(h){pS}2 (increase of phosphorylation) | TGF-beta3(h) --> TGFbeta3(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 74 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 135 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 142 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr14 |
Promoter: 75516742 - 75518742 | GoldenGate_Methylation_Cancer_Panel_I |
chr14 |
Promoter: 75516742 - 75518742 | GSE27584 |
chr14 |
Promoter: 75516742 - 75518742 | Agilent_014791_44K |