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Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

6670

Name

SP3

Synonymous

Sp3 transcription factor;SP3;Sp3 transcription factor

Definition

GC-binding transcription factor Sp3|specificity protein 3|transcription factor Sp3

Position

2q31

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

Sp3(h) --> HIV-1(HIV1) (DNA binding).
Sp3(h) --> CXCL1(h) (DNA binding).
Sp3(h) --> TP53(h) (DNA binding).
Sp3(h) --> E2F1(h) (DNA binding).
Sp3(h) --/ NKX2-1(h) (DNA binding; transrepression).
Sp3(h) --> FOSL1(h) (DNA binding; transactivation).
Sp3(h) --> PHOX2A(h) (DNA binding; transactivation).
Sp3(h) --> SP1(h) (DNA binding).
Sp3(h) --> SP-B(rb) (DNA binding; transactivation).
Sp3(h) --> AhRR(m) (DNA binding; transactivation).
Sp3(h) --/ NOS1(h) (DNA binding; transrepression).
Sp3(h) --> Oprm1(m) (DNA binding; transactivation).
Sp3(h) --> HSD17B1(h) (DNA binding; transactivation).
Sp3(h) --> KRT16(h) (DNA binding).
Sp3(h) --> HMOX1(h) (DNA binding).
Sp3(h) --> CCND1(h) (DNA binding).
Sp3(h) --> Scgb1a1(r) (DNA binding; transactivation).
Sp3(h) --> CYP2E1(rb) (DNA binding; transregulation).
Sp3(h) --> HAND1(h) (DNA binding).
Sp3(h) --/ MAOB(h) (DNA binding; transrepression).
Sp3(h) --/ LOR(h) (DNA binding; transrepression).
Sp3(h) --> TGFBR2(h) (DNA binding).
Sp3(h) --> TFAP2C(h) (DNA binding).
Sp3(h) --> Tcfap2c(m) (DNA binding).
Sp3(h) --> RET(h) (DNA binding).
Sp3(h) + acetyl-CoA --> Sp3(h){ace} + CoA (acetylation)
Sp3(h) + acetyl-CoA --CBP(h)--> Sp3(h){ace} + CoA (acetylation)
Sp3(h) --> SERPINE1(h) (DNA binding; transactivation).
Sp3(h) --> STAT1(h) (DNA binding).
Sp3(h) --> VEGFA(h) (DNA binding; transactivation).
Sp3(h) --> TFF1(h) (DNA binding).
Sp3(h) --> COL1A2(h) (DNA binding).
Sp3(h) --> CYP27A1(h) (DNA binding; transactivation).
Sp3(h) --> CYP4B1(h) (DNA binding; transactivation).
Sp3(h) --> HSD3B2(h) (DNA binding; transactivation).
Sp3(h) --> MYH7(h) (DNA binding).
Sp3(h) --> HSD3B1(h) (DNA binding).
Sp3(h) --> CYP17A1(h) (DNA binding; transactivation).
Sp3(h) --> HPSE(h) (DNA binding).
Sp3(h) --> COL2A1(h) (DNA binding).
Sp3(h) --> NQO2(h) (DNA binding).
Sp3(h) --> PTGES(h) (DNA binding).
Sp3(h) --> FN1(h) (DNA binding).
Sp3(h) --> CTSL(h) (DNA binding).
Sp3(h) --> HAS2(h) (DNA binding).
Sp3(h) --> PLA2G7(h) (DNA binding).
Sp3(h) + REST(h) <==> Sp3(h):REST(h) (binding)
Sp3(h) --> LPL(h) (DNA binding; transactivation).
Sp3(h) --> LDLR(h) (DNA binding).
Sp3(h) --> ITGAV(h) (DNA binding).
Sp3(h) --> CBS(h) (DNA binding).
Sp3(h) --> SLC19A1(h) (DNA binding).
Sp3(h) --> C4A(h) (DNA binding).
Sp3(h) --> EDF1(h) (DNA binding).
Sp3(h) --> ABCA2(h) (DNA binding; transactivation).
Sp3(h) --> SLC20A1(h) (DNA binding; transactivation).
Sp3(h) --> Acss2(m) (DNA binding).
Sp3(h) --> BSG(h) (DNA binding; transactivation).
Sp3(h) --> CYP3A4(h) (DNA binding).
Sp3(h) --> F2R(h) (DNA binding).
Sp3(h) --> INPPL1(h) (DNA binding).
Sp3(h) --> CYB5(h) (DNA binding; transactivation).
Sp3(h) --> CYP3A7(h) (DNA binding; transactivation).
Sp3(h) --> PROS1(h) (DNA binding).
Sp3(h) --> UTRN(h) (DNA binding; transactivation).
Sp3(h) --> PADI3(h) (DNA binding).
Sp3(h) --> MUC4(h) (DNA binding).
Sp3(h) --> ATP1A3(h) (DNA binding).
Sp3(h) --> TGM4(h) (DNA binding).
Sp3(h) --> RORA(m) (DNA binding).
Sp3(h) --> JARID1B(h) (DNA binding).
HDAC1(h) + Sp3(h) <==> HDAC1(h):Sp3(h) (binding)
hdac2(h) + Sp3(h) <==> hdac2(h):Sp3(h) (binding)
Sp3(h) --> CYP11A(b) (DNA binding).
Sp3(h) --> HOXB7(h) (DNA binding).
Sp3(h) --> EXO1(h) (DNA binding).
Sp3(h) --> CYP7B1(h) (DNA binding).
Sp3(h) --> CYP11A1(s) (DNA binding).
Sp3(h) --> Gabra4(m) (DNA binding).
Sp3(h) --> CDKN1A(h) (DNA binding).
Sp3(h) --> FASLG(h) (DNA binding).
Sp3(h) --> IRS2(h) (DNA binding).
Sp3(h) --> CDH2(h) (DNA binding).
Sp3(h) --> CYP2F1(h) (DNA binding).
p300(h) + Sp3(h) <==> p300(h):Sp3(h) (binding)
Sp3(h) --> IGFBP3(h) (transactivation)
Sp3(h) --> IL2RB(h) (DNA binding).
Sp3(h) --> BRCA1(h) (DNA binding).
Sp3(h) --> TLR2(h) (DNA binding).
Sp3(h) --> SSTR2(h) (DNA binding).
Sp3(h) --> BCL2L1(h) (DNA binding).
Sp3(h) --> ESR1(h) (DNA binding).
Sp3(h) --> FLT1(h) (DNA binding).
Sp3(h) --> HMGA1(h) (DNA binding).
Sp3(h) --> SSTR2(r) (DNA binding).
Sp3(h) --> SLC9A3(h) (DNA binding; transactivation)
Sp3(h) --> SLC9A2(h) (DNA binding).
Sp3(h) --> CDKN2C(h) (DNA binding).
Sp3(h) --> LAT(h) (DNA binding).
Sp3(h) --> ITGA11(h) (DNA binding).
Sp3(h) --> FOLR3(h) (DNA binding).
Sp3(h) --> MAOB(h) (DNA binding; transactivation).
Sp3(h) --> MMP2(h) (DNA binding).
Sp3(h) --> CAPNS1(h) (DNA binding).
Sp3(h) --> MYCN(h) (DNA binding).
Sp3(h) --> SP3(h) (DNA binding).
Sp3(h) --> CYP51A1(h) (DNA binding).
Sp3(h) --> Abcc10(h) (DNA binding).
Sp3(h) --> ULBP1(h) (DNA binding).
Sp3(h) --> DLC1(h) (DNA binding).
Sp3(h) --> LTC4S(h) (DNA binding).
Sp3(h) --> SCGB2A1(h) (DNA binding).
Sp3(h) --> KDR(h) (DNA binding).
Sp3(h) --> CXCL5(h) (DNA binding).
Sp3(h) --> HDAC4(h) (DNA binding).
Sp3(h) --> CHI3L1(h) (DNA binding; transactivation).
Sp3(h) --> P2RX1(h) (DNA binding).
Sp3(h) --> PDPN(h) (DNA binding).
Sp3(h) --> HSD17B2(h) (DNA binding).
Sp3(h) --> COL11A2(h) (DNA binding).
Sp3(h) --> KISS1(h) (DNA binding).
Sp3(h) --> ATF3(h) (transactivation)
Sp3(h) --> H2A.1(h) (transactivation)
Sp3(h) --> ACE(h) (transactivation)
Sp3(h) --> cdc25C(h) (DNA binding).
Sp3(h) --> CETP(h) (DNA binding).
Sp3(h) --> PGR(m) (DNA binding).
Sp3(h) --> SLC9A3(r) (DNA binding).
Sp3(h) --/ TCN2(h) (DNA binding; transrepression).
Sp3(h) --/ SCTR(h) (DNA binding; transrepression).
Sp3(h) --> CIDEA(h) (DNA binding).
Sp3(h) --/ TNC(h) (transrepression).
Sp3(h) --> PAPSS2(h) (DNA binding).
Sp3(h) --> DNASE2(h) (DNA binding).
Sp3(h) --> SOD3(h) (DNA binding).
hdac2(m.s.) + Sp3(h) <==> hdac2(m.s.):Sp3(h) (binding)
Sp3(h) --> IER3IP1(h) (transactivation)
Sp3(h) --> SV40(sv) (DNA binding).
Sp3(h) --> LTB(h) (DNA binding).
Sp3(h) --> IL12RB2(h) (DNA binding).
Sp3(h) --> ALOX12(h) (DNA binding).
Sp3(h) --> RASSF1(h) (DNA binding).
Sp3(h) --> GDF15(h) (DNA binding).
Sp3(h) --> IGFBP4(h) (DNA binding).
Sp3(h) --> TNFSF14(h) (DNA binding).
Sp3(h) --> APOBEC3G(h) (transactivation)
Sp3(h) --> SLC47A1(h) (DNA binding).
Sp3(h) --> Reg1a(r) (DNA binding).
Sp3(h) --> XYLT1(h) (transactivation)
Sp3(h) --> SLC19A3(h) (transactivation)
Sp3(h) --> HSPA5(h) (DNA binding).
Sp3(h) --> TCR-alpha(m) (DNA binding).
Sp3(h) --> Gata1(m) (DNA binding).
Sp3(h) --> uPA(h) (DNA binding).
Sp3(h) --> MC4R(h) (DNA binding).
Sp3(h) --> ITGB3(h) (DNA binding).
Sp3(h) --> CDKN2A(h) (DNA binding).
Sp3(h) --> PRDM1(h) (DNA binding).
Sp3(h) --> FBLN1(h) (DNA binding).
Sp3(h) --> TNFSF9(h) (DNA binding).
Sp3(h) --> EEF1A1(h) (DNA binding).
Sp3(h) --> Gp5(h) (DNA binding).
Sp3(h) --> ITGB8(h) (DNA binding).
Sp3(h) --> ITGAD(h) (DNA binding).
Sp3(h) --> LUM(h) (DNA binding).
Sp3(h) --> CYP46A1(h) (DNA binding).
Sp3(h) --> CGB5(h) (DNA binding).
SP3(h) --> Sp3(h) (expression).
Sp3-isoform1(h) --/ CYP1A1(r) (DNA binding; transrepression).
Sp3-isoform1(h) --> Hmga2(m) (DNA binding).
Sp3-isoform1(h) --> Il10(m) (DNA binding; transactivation).
Sp3-isoform1(h) --> Ug(rb) (DNA binding).
Sp3-isoform1(h) --> LCAT(h) (DNA binding; transactivation).
SP3(h) --> Sp3-isoform1(h) (expression).
SP3(h) --> Sp3-isoform5(h) (expression).
SP3(h) --> Sp3-isoform6(h) (expression).
SP3(h) --> Sp3-isoform2(h) (expression).
SP3(h) --> Sp3-isoform3(h) (expression).
SP3(h) --> Sp3-isoform4(h) (expression).

Post Translational Modification   [Top]

There is no record for SP3

Methylation Profile   [Top]

Chromosome

Location

Source

chr2

 Promoter: 174536693 - 174538693Agilent_014791

chr2

 Promoter: 174537809 - 174539809Agilent_014791

chr2

 Promoter: 174536693 - 174538693GSE27584

chr2

 Promoter: 174537809 - 174539809GSE27584

chr2

 Promoter: 174536693 - 174538693Agilent_014791_44K