| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6623 |
Name | SNCG |
Synonymous | synuclein, gamma (breast cancer-specific protein 1);SNCG;synuclein, gamma (breast cancer-specific protein 1) |
Definition | breast cancer-specific gene 1 protein|gamma-synuclein|persyn|synoretin |
Position | 10q23.2-q23.3 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | SNCG(h) --> gamma-synuclein(h) (expression). | gamma-synuclein(h) + ERK1(h) <==> gamma-synuclein(h):ERK1(h) (binding) | gamma-synuclein(h) + ERK2(h) <==> gamma-synuclein(h):ERK2(h) (binding) | gamma-synuclein(h) + JNK1(h) <==> gamma-synuclein(h):JNK1(h) (binding) | gamma-synuclein(h) --> ERK1(h){p} (increase of phosphorylation) | gamma-synuclein(h) --> ERK2(h){p} (increase of phosphorylation) | Hsp90(h) + Hsp70(h) + ER-alpha(h) + gamma-synuclein(h) <==> Hsp90(h):Hsp70(h):ER-alpha(h):gamma-synuclein(h) (binding) | Hsp70(h) + gamma-synuclein(h) <==> Hsp70(h):gamma-synuclein(h) (binding) | Hsc70(h) + gamma-synuclein(h) <==> Hsc70(h):gamma-synuclein(h) (binding) | BubR1(h) + gamma-synuclein(h) <==> BubR1(h):gamma-synuclein(h) (binding) | HNF-4alpha(h) + gamma-synuclein(h) <==> HNF-4alpha(h):gamma-synuclein(h) (binding) | exostosin-2(h) + gamma-synuclein(h) <==> exostosin-2(h):gamma-synuclein(h) (binding) | fabp4(h) + gamma-synuclein(h) <==> fabp4(h):gamma-synuclein(h) (binding) | SN-URF(h) + gamma-synuclein(h) <==> SN-URF(h):gamma-synuclein(h) (binding) | TIMP-2(h) + gamma-synuclein(h) <==> TIMP-2(h):gamma-synuclein(h) (binding) | gamma-synuclein(h) + LC8(h) <==> gamma-synuclein(h):LC8(h) (binding) | gamma-synuclein(h) + mcm3(h) <==> gamma-synuclein(h):mcm3(h) (binding) | gamma-synuclein(h) + FBP(h) <==> gamma-synuclein(h):FBP(h) (binding) | SNCG(h) --> gamma-synuclein(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 124 | Phosphoserine (by BARK1, CaMK2 and CK2). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr10 |
Promoter: 88706893 - 88708893 | GoldenGate_Methylation_Cancer_Panel_I |
chr10 |
Promoter: 88706893 - 88708893 | GSE27584 |
chr10 |
Promoter: 88706893 - 88708893 | PMID:12566312 |
chr10 |
Promoter: 88706893 - 88708893 | PMID:16816827 |