Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

6520

Name

SLC3A2

Synonymous

solute carrier family 3 (amino acid transporter heavy chain), member 2;SLC3A2;solute carrier family 3 (amino acid transporter heavy chain), member 2

Definition

4F2 cell-surface antigen heavy chain|CD98 heavy chain|antigen defined by monoclonal antibody 4F2, heavy chain|antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43|lymphocyte activation antigen 4F2 large subunit|monoclonal antibody 44D7

Position

11q13

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

SLC3A2(h) --> CD98(h) (expression).
CD98(h) + ErbB1(h) <==> CD98(h):ErbB1(h) (binding)
BRF-2(h) + CD98(h) <==> BRF-2(h):CD98(h) (binding)
hGSTK1(h) + CD98(h) <==> hGSTK1(h):CD98(h) (binding)
SLC3A2(h) --> CD98(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

2Phosphoserine.Swiss-Prot 53.0
5Phosphothreonine.Swiss-Prot 53.0
264N-linked (GlcNAc...).Swiss-Prot 53.0
280N-linked (GlcNAc...).Swiss-Prot 53.0
323N-linked (GlcNAc...).Swiss-Prot 53.0
405N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2Phosphoserine17081983Phospho.ELM 6.0
5Phosphothreonine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr11

Promoter: 62403363 - 62405363Agilent_014791

chr11

Promoter: 62378594 - 62380594GSE27584

chr11

Promoter: 62378594 - 62380594GSE27584

chr11

Promoter: 62378594 - 62380594GSE27584

chr11

Promoter: 62378594 - 62380594GSE27584

chr11

Promoter: 62403363 - 62405363GSE27584

chr11

Promoter: 62378594 - 62380594GSE27584

chr11

Promoter: 62378594 - 62380594Agilent_014791_44K