| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6352 |
Name | CCL5 |
Synonymous | chemokine (C-C motif) ligand 5;CCL5;chemokine (C-C motif) ligand 5 |
Definition | C-C motif chemokine 5|T-cell specific protein p288|beta-chemokine RANTES|eosinophil chemotactic cytokine|regulated upon activation, normally T-expressed, and presumably secreted|small inducible cytokine subfamily A (Cys-Cys), member 5 |
Position | 17q12 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | RANTES(h) --> Pyk2-isoform2(h) (activation; phosphorylation) | IGFBP-7(m) + RANTES(h) <==> IGFBP-7(m):RANTES(h) (binding) | CCL5(h) --> RANTES(h) (expression). | MAVS(h) --> RANTES(h) (increase of abundance) | TRIF(m.s.) --> RANTES(h) (increase of abundance) | TGFalpha(h) --/ RANTES(h) (decrease of abundance) | TNF-alpha{sol}(h) --> RANTES(h) (increase of secretion) | IL-1beta(m.s.) --> RANTES(h) (increase of secretion) | TNF-alpha(m.s.) --> RANTES(h) (increase of secretion) | IRAK1(m.s.) --> RANTES(h) (increase of secretion) | 3pRNA --> RANTES(h) (increase of secretion) | LPS(ECO) --> RANTES(h) (increase of secretion) | adiponectin(h) + RANTES(h) <==> adiponectin(h):RANTES(h) (binding) | CCL5(h) --> RANTES(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 27 | O-linked (GalNAc...); partial. | Swiss-Prot 53.0 | 28 | O-linked (GalNAc...); partial. | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
There is no record for CCL5 | ||