| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5976 |
Name | UPF1 |
Synonymous | UPF1 regulator of nonsense transcripts homolog (yeast);UPF1;UPF1 regulator of nonsense transcripts homolog (yeast) |
Definition | ATP-dependent helicase RENT1|delta helicase|nonsense mRNA reducing factor 1|regulator of nonsense transcripts 1|smg-2 homolog, nonsense mediated mRNA decay factor|up-frameshift mutation 1 homolog|up-frameshift suppressor 1 homolog|yeast Upf1p homolog |
Position | 19p13.11 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | RENT1(h) --> Upf1-isoform1(h) (expression). | Upf1(h) + Lsm8(h) <==> Upf1(h):Lsm8(h) (binding) | RENT1(h) --> Upf1(h) (expression). | Dom3(h) + Upf1-isoform2(h) <==> Dom3(h):Upf1-isoform2(h) (binding) | RENT1(h) --> Upf1-isoform2(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 1089 | Phosphoserine (Probable). | Swiss-Prot 53.0 | 1107 | Phosphoserine (Probable). | Swiss-Prot 53.0 | 1127 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 1107 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 1110 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr19 |
Promoter: 18802244 - 18804244 | GSE27584 |
chr19 |
Promoter: 18802244 - 18804244 | Agilent_014791_44K |