| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5888 |
Name | RAD51 |
Synonymous | RAD51 recombinase;RAD51;RAD51 recombinase |
Definition | BRCA1/BRCA2-containing complex, subunit 5|DNA repair protein RAD51 homolog 1|RAD51 homolog A|RecA, E. coli, homolog of|RecA-like protein|recombination protein A |
Position | 15q15.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | brca1(h) + Rad51(h) <==> brca1(h):Rad51(h) (binding) | Rad51(h) --Caspase-3(h)--> protein remnants (processing) | Rad51(h) + ATM(v.s.) <==> Rad51(h):ATM(v.s.) (binding) | Rad51(h) + Abl(v.s.) <==> Rad51(h):Abl(v.s.) (binding) | Rad51(h) + ATP --Abl(v.s.)--> Rad51(h){pY315} + ADP (phosphorylation) | Rad52(h) + Rad51(h) <==> Rad51(h):Rad52(h) (binding) | Rad51(h) + BRCA2(h){pS193}{p}2 <==> Rad51(h):BRCA2(h){pS193}{p}2 (binding) | Rad51(h) + BRCA2(h){p} <==> Rad51(h):BRCA2(h){p} (binding) | Rad51(h) + RecQ4(h) <==> Rad51(h):RecQ4(h) (binding) | Pir51(h) + Rad51(h) <==> Pir51(h):Rad51(h) (binding) | Rad54B(h) + Rad51(h) <==> Rad54B(h):Rad51(h) (binding) | Rad51(h) + mcm3(h) <==> Rad51(h):mcm3(h) (binding) | RPA1(h):RPA2(h):RPA3(h) + Rad51(h) <==> RPA1(h):RPA2(h):RPA3(h):Rad51(h) (binding) | Rad51(h) + RPA1(h) <==> Rad51(h):RPA1(h) (binding) | Rad51(h) + RAD51C(h):XRCC3(h) <==> Rad51(h):RAD51C(h):XRCC3(h) (binding) | RAD51C(h) + Rad51(h) <==> RAD51C(h):Rad51(h) (binding) | Rad51(h) + RAD51C(h) <==> Rad51(h):RAD51C(h) (binding) | GTBP(h) + Rad51(h) <==> GTBP(h):Rad51(h) (binding) | Rad51(h) + MSH2(h) <==> Rad51(h):MSH2(h) (binding) | Rad51(h) + Rad51B(h):RAD51C(h):Rad51D(h):XRCC2(h) <==> Rad51(h):Rad51B(h):RAD51C(h):Rad51D(h):XRCC2(h) (binding) | Rad51(h) + BLM(h) <==> Rad51(h):BLM(h) (binding) | p53(h) + Rad51(h) <==> p53(h):Rad51(h) (binding) | Palb2(h) + BRCA2(h) + Rad51(h) <==> Palb2(h):BRCA2(h):Rad51(h) (binding) | Rad51(h) + BRCA2(m.s.) <==> Rad51(h):BRCA2(m.s.) (binding) | BRE(h) + BRCC36(h) + Rad51(h) + BRCA2(h) + brca1(h) + BARD1(m.s.) <==> BARD1(m.s.):brca1(h):BRCA2(h):BRCC36(h):BRE(h):Rad51(h) (binding) | BRCA2(h) + Rad51(h) <==> BRCA2(h):Rad51(h) (binding) | Rad51(h) + HCA56(h) <==> Rad51(h):HCA56(h) (binding) | Rad51(h) + MO25(h) <==> Rad51(h):MO25(h) (binding) | Rad51(h) + TIM13(h) <==> Rad51(h):TIM13(h) (binding) | Rad51(h) + CLEC2L(h) <==> Rad51(h):CLEC2L(h) (binding) | Rad51(h) + obfc2b(h) <==> Rad51(h):obfc2b(h) (binding) | Rad51(h) + Mi2-alpha(h) <==> Rad51(h):Mi2-alpha(h) (binding) | Rad51(h) + vimentin(h) <==> Rad51(h):vimentin(h) (binding) | RAD51(h) --> Rad51(h) (expression). | Pir51-isoform1(h) + Rad51(h) <==> Pir51-isoform1(h):Rad51(h) (binding) | Rad51(h) + Pir51(h) <==> Rad51(h):Pir51(h) (binding) | Rad51(h) + Rad52(h) <==> Rad51(h):Rad52(h) (binding) | 2 Rad51(h) <==> (Rad51(h))2 (oligomerization) | Rad51(h) + 2 ATP --Abl(m.s.)--> Rad51(h){pY54}{pY315} + 2 ADP (phosphorylation) | RAD51(h) --> Rad51(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 309 | Phosphothreonine (by CHK1). | Swiss-Prot 53.0 | 54 | Phosphotyrosine (Abl) | 9461559 | Phospho.ELM 6.0 | 309 | Phosphothreonine | 15665856 | Phospho.ELM 6.0 | 315 | Phosphotyrosine (Abl) | 11684015;10212258 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr15 |
Promoter: 38773161 - 38775161 | Agilent_014791 |
chr15 |
Promoter: 38773161 - 38775161 | GSE27584 |
chr15 |
Promoter: 38773161 - 38775161 | GSE27584 |
chr15 |
Promoter: 38773161 - 38775161 | Agilent_014791_44K |
chr15 |
Promoter: 38773161 - 38775161 | Agilent_014791 |