| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5774 |
Name | PTPN3 |
Synonymous | protein tyrosine phosphatase, non-receptor type 3;PTPN3;protein tyrosine phosphatase, non-receptor type 3 |
Definition | cytoskeletal-associated protein tyrosine phosphatase|protein-tyrosine phosphatase H1|tyrosine-protein phosphatase non-receptor type 3 |
Position | 9q31 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | ptpn3(h) + CD3zeta(m.s.) <==> ptpn3(h):CD3zeta(m.s.) (binding) | ptpn3(h) --/ IGF1(h) (transrepression) | 14-3-3sigma(m.s.) + ptpn3(h) <==> 14-3-3sigma(m.s.):ptpn3(h) (binding) | PTPN3(h) --> ptpn3(h) (expression). | CD3zeta(m.s.){p} --ptpn3(h)--> CD3zeta(m.s.) + p (dephosphorylation) | PTPN3(h) --> ptpn3(h) (expression). | GHR(rb){pY} --ptpn3(h)--> GHR(rb) + p (dephosphorylation) | STAT5(h){pY} --ptpn3(h)--> STAT5(h) + p (dephosphorylation) |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 359 | Phosphoserine (MAP3K7) | 9341175 | Phospho.ELM 6.0 | 835 | Phosphoserine | 9341175 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
There is no record for PTPN3 | ||