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Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

573

Name

BAG1

Synonymous

BCL2-associated athanogene;BAG1;BCL2-associated athanogene

Definition

BAG family molecular chaperone regulator 1|Bcl-2 associating athanogene-1 protein|Bcl-2-binding protein|glucocortoid receptor-associated protein RAP46|receptor-associated protein, 46-KD

Position

9p12

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

bag1-xbb1(h) + Hsc70(b) <==> bag1-xbb1(h):Hsc70(b) (binding)
bag1-xbb1(h) + Hsc70(r) <==> bag1-xbb1(h):Hsc70(r) (binding)
bag1-xbb1(h) + GR(m) <==> bag1-xbb1(h):GR(m) (binding)
bag1-xbb1(h) + T3R-beta1(h) <==> bag1-xbb1(h):T3R-beta1(h) (binding)
bag1-xbb1(h) + AR(h) <==> bag1-xbb1(h):AR(h) (binding)
bag1-xbb1(h) + ER(h) <==> bag1-xbb1(h):ER(h) (binding)
BAG1(h) --> bag1-xbb1(h) (expression).
bag1-isoform1(h) --> NR3C1(h) (transactivation)
bag1-isoform1(h) --> ER(h) (activation; expression)
bag1-isoform1(h) --> JUN(h) (transactivation)
bag1-isoform1(h) --> FOS(h) (transactivation)
bag1-isoform1(h) + VDR(h) <==> bag1-isoform1(h):VDR(h) (binding)
BAG1(h) --> bag1-isoform1(h) (expression).
bag1(h) + CHIP(m.s.) <==> bag1(h):CHIP(m.s.) (binding)
bag1(h) + ER-alpha(m.s.) <==> bag1(h):ER-alpha(m.s.) (binding)
ER-alpha(h) + bag1(h) <==> ER-alpha(h):bag1(h) (binding)
bag1(h) + ubiquitin(h) --> bag1(h){ub} (ubiquitination)
bag1(h) + n ubiquitin(h) --> bag1(h){ub}n (ubiquitination)
bag1(h) + ubiquitin(rb) --E1(rb)--> bag1(h){ub} (ubiquitination)
bag1(h) + ubiquitin(h) --E1(rb),Ubc5B(h),CHIP(h)--> bag1(h){ub} (ubiquitination)
bag1(h) + 2 ubiquitin(h) --E1(rb),Ubc5B(h),CHIP(h)--> bag1(h){ub(2)} (ubiquitination)
bag1(h) + n ubiquitin(h) --CHIP(h)--> bag1(h){ub(n)K11} (ubiquitination)
bag1(h) + n ubiquitin(h) --Ubc5B(h),CHIP(h),Hsc70(r),Hsp40(h)--> bag1(h){ub(n)K11} (ubiquitination)
ER-alpha-L(h) + bag1(h) <==> ER-alpha-L(h):bag1(h) (binding)
Hsp70(h):Hsc70(h) + bag1(h) <==> Hsp70(h):Hsc70(h):bag1(h) (binding)
bag1(h) --/ bag3(h) (decrease of abundance)
BAG1(h) --> bag1(h) (expression).
bag3(h) --/ bag1(h) (decrease of abundance)
BAG1(h) --> bag1-isoform2(h) (expression).

Post Translational Modification   [Top]

There is no record for BAG1

Methylation Profile   [Top]

Chromosome

Location

Source

chr9

Promoter: 33254261 - 33256261GSE27584

chr9

Promoter: 33254261 - 33256261Agilent_014791_44K