Entrez Gene

Basic Information
Gene ID	572
Name	BAD
Synonymous	BCL2-associated agonist of cell death;BAD;BCL2-associated agonist of cell death
Definition	BCL-X/BCL-2 binding protein\|BCL2-antagonist of cell death protein\|BCL2-binding component 6\|BCL2-binding protein\|bcl-2-binding component 6\|bcl-2-like protein 8\|bcl-XL/Bcl-2-associated death promoter\|bcl2 antagonist of cell death\|bcl2-L-8\|bcl2-associated ag
Position	11q13.1
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
bad(h) + ATP --p65PAK(h)--> ADP + bad(h){pS} (phosphorylation)
bad(h) + Bcl-2(h) <==> bad(h):Bcl-2(h) (binding)
bad(h) + Bcl-X(h) <==> bad(h):Bcl-X(h) (binding)
bad(h) + ATP --AKT(v.s.)--> bad(h){pS} + ADP (phosphorylation)
bad(h) + ATP --Raf-1(h)--> bad(h){pS} + ADP (phosphorylation)
bad(h) + ATP --PKAc(v.s.)--> bad(h){pS} + ADP (phosphorylation)
bad(h) + ATP --> bad(h){pS75} + ADP (phosphorylation)
bad(h) + ATP --> bad(h){pS99} + ADP (phosphorylation)
bad(h) + 3 ATP --PKCiota(h)--> bad(h){pS75}{pS99}{pS118} + 3 ADP (phosphorylation)
p53(h) + bad(h) <==> p53(h):bad(h) (binding)
c-Jun(h) + bad(h) <==> c-Jun(h):bad(h) (binding)
bad(h) + EWS(h) <==> bad(h):EWS(h) (binding)
bad(h) + 14-3-3sigma(h) <==> bad(h):14-3-3sigma(h) (binding)
bad(h) + 14-3-3beta(h) <==> bad(h):14-3-3beta(h) (binding)
bad(h) + 2 ATP --> bad(h){pS118}{pS134} + 2 ADP (phosphorylation)
bad(h) + ATP --> bad(h){pS} + ADP (phosphorylation)
BAD(h) --> bad(h) (expression).
bad(h){pS} --calcineurin(v.s.)--> bad(h) + p (dephosphorylation)
p53(h) --> bad(h) (increase of abundance)
p53(m.s.) --> bad(h) (increase of abundance)
p75NTR(m.s.) --> bad(h) (increase of abundance)
bad(h) + ATP --> bad(h){pS134} + ADP (phosphorylation)
BAD(h) --> bad(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
75	Phosphoserine (by PKA and PKB) (Bysimilarity).		Swiss-Prot 53.0
99	Phosphoserine (by PKA and PKB) (Bysimilarity).		Swiss-Prot 53.0
118	Phosphoserine (by PKA and PKB) (Bysimilarity).		Swiss-Prot 53.0
134	Phosphoserine (By similarity).		Swiss-Prot 53.0
75	Phosphoserine (MAPK14;RSK-1)	10837486;15037618;15972258;15226424	Phospho.ELM 6.0
118	Phosphoserine (RSK-1)	10837486	Phospho.ELM 6.0

Transcription Factors [Top]