| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 57144 |
Name | PAK7 |
Synonymous | p21 protein (Cdc42/Rac)-activated kinase 7;PAK7;p21 protein (Cdc42/Rac)-activated kinase 7 |
Definition | PAK-5|PAK-7|p21(CDKN1A)-activated kinase 7|p21-activated kinase 5|p21-activated kinase 7|p21CDKN1A-activated kinase 7|protein kinase PAK5|serine/threonine-protein kinase PAK 7|serine/threonine-protein kinase PAK7 |
Position | 20p12 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | pak7(h) + Rac1(m.s.):GTP <==> pak7(h):Rac1(m.s.):GTP (binding) | Cdc42(m.s.):GTP + pak7(h) <==> Cdc42(m.s.):GTP:pak7(h) (binding) | pak7(h) + ATP --> pak7(h){p} + ADP (phosphorylation; automodification) | PAK7(h) --> pak7(h) (expression). | pak7(h) + MRP-14(h) <==> pak7(h):MRP-14(h) (binding) | pak7(h) + HIG1(h) <==> pak7(h):HIG1(h) (binding) | pak7(h) + Psoriasin(h) <==> pak7(h):Psoriasin(h) (binding) | pak7(h) + RPA3(h) <==> pak7(h):RPA3(h) (binding) | pak7(h) + sigma-adaptin(h) <==> pak7(h):sigma-adaptin(h) (binding) | pak7(h) + CCDC59(h) <==> pak7(h):CCDC59(h) (binding) | Slim-2(h) + pak7(h) <==> Slim-2(h):pak7(h) (binding) | LMP(h) + pak7(h) <==> LMP(h):pak7(h) (binding) | GCP-4(h) + pak7(h) <==> GCP-4(h):pak7(h) (binding) | pak7(h) + lzts2(h) <==> pak7(h):lzts2(h) (binding) | PAK7(h) --> pak7(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 104 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 107 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 573 | Phosphoserine (PAK5) | 11756552 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr20 |
Promoter: 9767022 - 9769022 | Agilent_014791 |
chr20 |
Promoter: 9767022 - 9769022 | GSE27584 |
chr20 |
Promoter: 9767022 - 9769022 | GSE27584 |
chr20 |
Promoter: 9767022 - 9769022 | Agilent_014791_44K |
chr20 |
Promoter: 9767022 - 9769022 | Agilent_014791_44K |