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Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

56288

Name

PARD3

Synonymous

par-3 family cell polarity regulator;PARD3;par-3 family cell polarity regulator

Definition

CTCL tumor antigen se2-5|PAR3-alpha|atypical PKC isotype-specific interacting protein|atypical PKC isotype-specific-interacting protein|bazooka|par-3 family cell polarity regulator alpha|par-3 partitioning defective 3 homolog|partitioning defective 3 homo

Position

10p11.21

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

PARD3(h) --> Par3-isoform1(h) (expression).
14-3-3beta(h) + Par3(h) <==> 14-3-3beta(h):Par3(h) (binding)
14-3-3gamma(h) + Par3(h) <==> 14-3-3gamma(h):Par3(h) (binding)
14-3-3sigma(m.s.) + Par3(h) <==> 14-3-3sigma(m.s.):Par3(h) (binding)
PARD3(h) --> Par3(h) (expression).
PARD3(h) --> Par3-isoform2(h) (expression).
PARD3(h) --> Par3-isoform3(h) (expression).
PARD3(h) --> Par3-isoform4(h) (expression).
PARD3(h) --> Par3-isoform5(h) (expression).
PARD3(h) --> Par3-isoform6(h) (expression).
PARD3(h) --> Par3-isoform7(h) (expression).
PARD3(h) --> Par3-isoform8(h) (expression).
PARD3(h) --> Par3-isoform9(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

144Phosphoserine.Swiss-Prot 53.0
383Phosphoserine.Swiss-Prot 53.0
717Phosphoserine (By similarity).Swiss-Prot 53.0
827Phosphoserine (By similarity).Swiss-Prot 53.0
1127Phosphotyrosine.Swiss-Prot 53.0
383Phosphoserine15302935Phospho.ELM 6.0
144Phosphoserine14653998;17081983Phospho.ELM 6.0
889Phosphoserine15721295Phospho.ELM 6.0
1127Phosphotyrosine15951569Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr10

Promoter: 35143429 - 35145429Agilent_014791

chr10

Promoter: 35143429 - 35145429GSE27584

chr10

Promoter: 35143429 - 35145429Agilent_014791_44K