| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5339 |
Name | PLEC |
Synonymous | plectin;PLEC;plectin |
Definition | hemidesmosomal protein 1|plectin 1, intermediate filament binding protein 500kDa |
Position | 8q24 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | PLEC1(h) --> plectin-isoform1(h) (expression). | beta2-spectrin(h) + lamin B(h) + actin(h) + vimentin(h) + plectin(h) <==> beta2-spectrin(h):lamin B(h):actin(h):vimentin(h):plectin(h) (binding) | plectin(h) + moesin(h) + beta2-spectrin(h) + actin(h) + vimentin(h) <==> plectin(h):moesin(h):beta2-spectrin(h):actin(h):vimentin(h) (binding) | vimentin(h) + actin(h) + beta2-spectrin(h) + plectin(h) <==> vimentin(h):actin(h):beta2-spectrin(h):plectin(h) (binding) | PLEC1(h) --> plectin(h) (expression). |
|---|
Post Translational Modification [Top] | |||
There is no record for PLEC | |||
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr8 |
Promoter: 145119128 - 145121128 | GSE27584 |
chr8 |
Promoter: 145099576 - 145101576 | GSE27584 |
chr8 |
Promoter: 145096532 - 145098532 | GSE27584 |
chr8 |
Promoter: 145090393 - 145092393 | GSE27584 |
chr8 |
Promoter: 145089553 - 145091553 | GSE27584 |
chr8 |
Promoter: 145088180 - 145090180 | GSE27584 |
chr8 |
Promoter: 145085246 - 145087246 | GSE27584 |
chr8 |
Promoter: 145121031 - 145123031 | GSE27584 |