Entrez Gene

Basic Information
Gene ID	5293
Name	PIK3CD
Synonymous	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta;PIK3CD;phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Definition	PI3-kinase p110 subunit delta\|PI3Kdelta\|phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform\|phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta\|phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic
Position	1p36.2
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
PIK3CD(h) --> p110delta(h) (expression).
p85beta(h) + p110delta(h) <==> p85beta(h):p110delta(h) (binding)
p85alpha(h) + p110delta(h) <==> p85alpha(h):p110delta(h) (binding)
p55gamma(b) + p110delta(h) <==> p55gamma(b):p110delta(h) (binding)
p110delta(h) + ATP --> p110delta(h){pS} + ADP (phosphorylation; automodification)
PIK3CD(h) --> p110delta(h) (expression).
PtdIns + ATP --p110delta(h)--> PtdIns(3)P + ADP
PtdIns(4)P + ATP --p110delta(h)--> PtdIns(3,4)P2 + ADP

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
1039	Phosphoserine (by autocatalysis).		Swiss-Prot 53.0
1039	Phosphoserine (PIK3CD)	10064595	Phospho.ELM 6.0
440	Phosphotyrosine	16497976	Phospho.ELM 6.0
524	Phosphotyrosine	16497976	Phospho.ELM 6.0
485	Phosphotyrosine	16497976	Phospho.ELM 6.0

Transcription Factors [Top]