| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5054 |
Name | SERPINE1 |
Synonymous | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1;SERPINE1;serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
Definition | endothelial plasminogen activator inhibitor|plasminogen activator inhibitor 1|serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1|serpin E1 |
Position | 7q22.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | p53(h) --> PAI1(h) (increase of abundance) | SERPINE1(h) --> PAI1(h) (expression). | TGFbeta2(h) --> PAI1(h) (increase of abundance) | SERPINE1(h) --> PAI1(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 232 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 288 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 352 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr7 |
Promoter: 100555672 - 100557672 | GoldenGate_Methylation_Cancer_Panel_I |
chr7 |
Promoter: 100555672 - 100557672 | GSE27584 |
chr7 |
Promoter: 100555672 - 100557672 | Agilent_014791 |