| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5008 |
Name | OSM |
Synonymous | oncostatin M;OSM;oncostatin M |
Definition | oncostatin-M |
Position | 22q12.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | OSM(h) --> STAT5(h){pY} (increase of phosphorylation) | OSM(h) --> STAT3(h){pY705} (increase of phosphorylation) | OSM(h) --> STAT3(h){pY} (increase of phosphorylation) | OSM(h) --> OSM(h) (expression). | OSM(h) --> c-myc(h) (transactivation) | OSM(h) --> FOS(h) (transactivation) | OSM(h) --> CEBPD(h) (transactivation) | OSM(h) --> STAT3(h){p} (increase of phosphorylation) | OSM(h) --> C/EBPdelta(h) (increase of abundance) | OSM(h) --> STAT1(h){pY701}{pS727} (increase of phosphorylation) | OSM(h) --> LIFR(m){pY} (increase of phosphorylation) | OSM(h) --> STAT3(m){pY705} (increase of phosphorylation) | OSM(h) --> Jak1(m.s.){pY} (increase of phosphorylation) | OSM(h) --> STAT1(h){pY701} (increase of phosphorylation) | OSM(h) --> OSM(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 100 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 217 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr22 |
Promoter: 28992340 - 28994340 | GoldenGate_Methylation_Cancer_Panel_I |
chr22 |
Promoter: 28992340 - 28994340 | GSE27584 |