| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4929 |
Name | NR4A2 |
Synonymous | nuclear receptor subfamily 4, group A, member 2;NR4A2;nuclear receptor subfamily 4, group A, member 2 |
Definition | NGFI-B/nur77 beta-type transcription factor homolog|T-cell nuclear receptor NOT|immediate-early response protein NOT|intermediate-early receptor protein|nuclear receptor related 1|nuclear receptor subfamily 4 group A member 2|nur related protein-1, human |
Position | 2q22-q23 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | NURR1(h) --> CYP11B2(h) (DNA binding). | NURR1(h) + JAB1(h) <==> NURR1(h):JAB1(h) (binding) | NURR1(h) + RXR-beta(h) <==> NURR1(h):RXR-beta(h) (binding) | NURR1(h) + RXR-alpha(h) <==> NURR1(h):RXR-alpha(h) (binding) | NURR1(h) --> CRH(h) (DNA binding). | NR4A2(h) --> NURR1(h) (expression). | NURR1(h) + ERK1(h) <==> NURR1(h):ERK1(h) (binding) | NURR1(h) + ERK2(h) <==> NURR1(h):ERK2(h) (binding) | NURR1(h) + ERK2(m.s.) <==> NURR1(h):ERK2(m.s.) (binding) | NURR1(h) + ATP --ERK2(m.s.)--> NURR1(h){pS126}{pT129}{pT132}{pT185} + ADP (phosphorylation) | NURR1(h) --> tyrosine 3-monooxygenase(h) (increase of abundance) | NURR1(h) --> SLC6A3(h) (DNA binding). | NR4A2(h) --> NURR1(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 181 | Phosphoserine. | Swiss-Prot 53.0 | 181 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr2 |
Promoter: 156896946 - 156898946 | Agilent_014791 |
chr2 |
Promoter: 156896946 - 156898946 | GSE27584 |