| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4644 |
Name | MYO5A |
Synonymous | myosin VA (heavy chain 12, myoxin);MYO5A;myosin VA (heavy chain 12, myoxin) |
Definition | dilute myosin heavy chain, non-muscle|myosin V|myosin, heavy polypeptide kinase|myosin-12|myosin-Va|myoxin|unconventional myosin-Va |
Position | 15q21 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | MYO5A(h) --> Myosin-5A-isoform1(h) (expression). | Myosin-5A(h) + Melanophilin(m) <==> Myosin-5A(h):Melanophilin(m) (binding) | Myosin-5A(h) --> RAB27A(h) (increase of abundance) | MYO5A(h) --> Myosin-5A(h) (expression). | RAB27A(m) + Myosin-5A-isoform2(h) <==> RAB27A(m):Myosin-5A-isoform2(h) (binding) | Myosin-5A-isoform2(h) + Melanophilin-isoform1(h) <==> Myosin-5A-isoform2(h):Melanophilin-isoform1(h) (binding) | MYO5A(h) --> Myosin-5A-isoform2(h) (expression). | MYO5A(h) --> Myosin-5A-isoform3(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 600 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 1213 | Phosphoserine. | Swiss-Prot 53.0 | 1760 | Phosphothreonine (Potential). | Swiss-Prot 53.0 | 1213 | Phosphoserine | 16097034 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr15 |
Promoter: 50608039 - 50610039 | Agilent_014791 |
chr15 |
Promoter: 50608039 - 50610039 | GSE27584 |