| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4162 |
Name | MCAM |
Synonymous | melanoma cell adhesion molecule;MCAM;melanoma cell adhesion molecule |
Definition | Gicerin|S-endo 1 endothelial-associated antigen|cell surface glycoprotein MUC18|cell surface glycoprotein P1H12|melanoma adhesion molecule|melanoma-associated antigen A32|melanoma-associated antigen MUC18 |
Position | 11q23.3 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | MCAM(h) --> mcam-isoform1(h) (expression). | MCAM(h) --> mcam(h) (expression). | ET-1(m.s.) --> mcam(h) (increase of abundance) | ET3(m.s.) --> mcam(h) (increase of abundance) |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 56 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 418 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 449 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 467 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 508 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 518 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 527 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 544 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 614 | Phosphoserine. | Swiss-Prot 53.0 | 614 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr11 |
Promoter: 118692550 - 118694550 | Agilent_014791 |
chr11 |
Promoter: 118692550 - 118694550 | GoldenGate_Methylation_Cancer_Panel_I |
chr11 |
Promoter: 118692550 - 118694550 | GSE27584 |
chr11 |
Promoter: 118692550 - 118694550 | Agilent_014791_44K |