| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4152 |
Name | MBD1 |
Synonymous | methyl-CpG binding domain protein 1;MBD1;methyl-CpG binding domain protein 1 |
Definition | CXXC-type zinc finger protein 3|methyl-CpG binding domain protein 1 isoform PCM1|methyl-CpG-binding domain protein 1|protein containing methyl-CpG-binding domain 1|the regulator of fibroblast growth factor 2 (FGF-2) transcription |
Position | 18q21 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | MBD1(h) --> CHAF1A(h) (binding) | MBD1(h) --> PCNA(h) (binding) | MBD1(h) + sumo1(h) --> MBD1(h){sumo} (sumoylation) | MBD1(h) --> MAGEA1(h) (DNA binding). | MBD1(h) --> MAGEA3(h) (DNA binding). | MBD1(h) --> MAGEA12(h) (DNA binding). | MBD1(h) --> MAGEA2B(h) (DNA binding). | MBD1(h) --> MBD1(h) (expression). | MBD1-isoform1(h) + sumo3(m.s.) --> MBD1-isoform1(h){sumo3} (sumoylation) | MBD1(h) --> MBD1-isoform1(h) (expression). | MBD1(h) --> MBD1-isoform2(h) (expression). | MBD1(h) --> MBD1-isoform3(h) (expression). | MBD1(h) --> MBD1-isoform4(h) (expression). | MBD1(h) --> MBD1-isoform5(h) (expression). | MBD1(h) --> MBD1-isoform6(h) (expression). | MBD1(h) --> MBD1-isoform7(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 52 | Phosphotyrosine. | Swiss-Prot 53.0 | 499 | Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO). | Swiss-Prot 53.0 | 538 | Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO). | Swiss-Prot 53.0 | 52 | Phosphotyrosine | 16094384 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr18 |
Promoter: 46061344 - 46063344 | Agilent_014791 |
chr18 |
Promoter: 46061344 - 46063344 | GSE27584 |
chr18 |
Promoter: 46061344 - 46063344 | GSE27584 |
chr18 |
Promoter: 46061344 - 46063344 | GSE27584 |
chr18 |
Promoter: 46061344 - 46063344 | GSE27584 |
chr18 |
Promoter: 46061344 - 46063344 | GSE27584 |