Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

4152

Name

MBD1

Synonymous

methyl-CpG binding domain protein 1;MBD1;methyl-CpG binding domain protein 1

Definition

CXXC-type zinc finger protein 3|methyl-CpG binding domain protein 1 isoform PCM1|methyl-CpG-binding domain protein 1|protein containing methyl-CpG-binding domain 1|the regulator of fibroblast growth factor 2 (FGF-2) transcription

Position

18q21

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

MBD1(h) --> CHAF1A(h) (binding)
MBD1(h) --> PCNA(h) (binding)
MBD1(h) + sumo1(h) --> MBD1(h){sumo} (sumoylation)
MBD1(h) --> MAGEA1(h) (DNA binding).
MBD1(h) --> MAGEA3(h) (DNA binding).
MBD1(h) --> MAGEA12(h) (DNA binding).
MBD1(h) --> MAGEA2B(h) (DNA binding).
MBD1(h) --> MBD1(h) (expression).
MBD1-isoform1(h) + sumo3(m.s.) --> MBD1-isoform1(h){sumo3} (sumoylation)
MBD1(h) --> MBD1-isoform1(h) (expression).
MBD1(h) --> MBD1-isoform2(h) (expression).
MBD1(h) --> MBD1-isoform3(h) (expression).
MBD1(h) --> MBD1-isoform4(h) (expression).
MBD1(h) --> MBD1-isoform5(h) (expression).
MBD1(h) --> MBD1-isoform6(h) (expression).
MBD1(h) --> MBD1-isoform7(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

52Phosphotyrosine.Swiss-Prot 53.0
499Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO).Swiss-Prot 53.0
538Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO).Swiss-Prot 53.0
52Phosphotyrosine16094384Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr18

Promoter: 46061344 - 46063344Agilent_014791

chr18

Promoter: 46061344 - 46063344GSE27584

chr18

Promoter: 46061344 - 46063344GSE27584

chr18

Promoter: 46061344 - 46063344GSE27584

chr18

Promoter: 46061344 - 46063344GSE27584

chr18

Promoter: 46061344 - 46063344GSE27584