| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3934 |
Name | LCN2 |
Synonymous | lipocalin 2;LCN2;lipocalin 2 |
Definition | 25 kDa alpha-2-microglobulin-related subunit of MMP-9|lipocalin-2|migration-stimulating factor inhibitor|neutrophil gelatinase-associated lipocalin|oncogene 24p3|p25|siderocalin LCN2 |
Position | 9q34 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | Megalin(h) + lipocalin2(h) <==> Megalin(h):lipocalin2(h) (binding) | LCN2(h) --> lipocalin2(h) (expression). | FOXO3a(m.s.) --> lipocalin2(h) (increase of abundance) | IL-3(m.s.) --/ lipocalin2(h) (decrease of abundance) | LCN2(h) --> lipocalin2(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 21 | Pyrrolidone carboxylic acid. | Swiss-Prot 53.0 | 85 | N-linked (GlcNAc...). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr9 |
Promoter: 129950053 - 129952053 | GoldenGate_Methylation_Cancer_Panel_I |
chr9 |
Promoter: 129950053 - 129952053 | GSE27584 |