Entrez Gene

Basic Information
Gene ID	3925
Name	STMN1
Synonymous	stathmin 1;STMN1;stathmin 1
Definition	leukemia-associated phosphoprotein p18\|metablastin\|oncoprotein 18\|phosphoprotein 19\|phosphoprotein p19\|prosolin\|stathmin\|stathmin 1/oncoprotein 18\|transmembrane protein C1orf215
Position	1p36.11
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
stathmin(h) + NTP --p65PAK(m)--> stathmin(h){pS16} + NDP (phosphorylation)
stathmin(h) + ATP --CAMKII(r)--> stathmin(h){pS16} + ADP (phosphorylation)
stathmin(h) + 2 ATP --p38delta(h){p}--> stathmin(h){pS25}{pS38} + 2 ADP (phosphorylation)
stathmin(h) + 2 ATP --p38gamma(h){p}--> stathmin(h){pS25}{pS38} + 2 ADP (phosphorylation)
stathmin(h) + 2 ATP --ERK2(v.s.){p}--> stathmin(h){pS25}{pS38} + 2 ADP (phosphorylation)
stathmin(h) + 2 ATP --ERK2(ss)--> stathmin(h){pS25}{pS38} + 2 ADP (phosphorylation)
stathmin(h) + ATP --Cdk1(ss)--> stathmin(h){pS38} + ADP (phosphorylation)
stathmin(h) + ATP --CKII(ss)--> stathmin(h){pT146} + ADP (phosphorylation)
stathmin(h) + KIS(m) <==> stathmin(h):KIS(m) (binding)
stathmin(h) + GRP78(m) <==> stathmin(h):GRP78(m) (binding)
stathmin(h) + ATP --KIS(r)--> stathmin(h){p} + ADP (phosphorylation)
stathmin(h) + ATP --PKAc(b)--> stathmin(h){pS16}{pS63} + ADP (phosphorylation)
stathmin(h) + 2 ATP --Cdk1(v.s.)--> stathmin(h){pS25}{pS38} + 2 ADP (phosphorylation)
STMN1(h) --> stathmin(h) (expression).
STMN1(h) --> STMN1(h) (expression).
hsa-miR-223 --/ STMN1(h) (translational repression).
STMN1(h) --> stathmin(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
2	N-acetylalanine.		Swiss-Prot 53.0
16	Phosphoserine.		Swiss-Prot 53.0
25	Phosphoserine (by CDK1 and MAPK).		Swiss-Prot 53.0
38	Phosphoserine (by CDK1).		Swiss-Prot 53.0
46	Phosphoserine (By similarity).		Swiss-Prot 53.0
63	Phosphoserine (by PKA).		Swiss-Prot 53.0
37	Phosphoserine (MAPK13;PKC b)	93315482;8245003;9731215;8325881;17081983	Phospho.ELM 6.0
15	Phosphoserine (PAK1)	94064639;10913145;8245003;7925472;17081983	Phospho.ELM 6.0

Transcription Factors [Top]