Entrez Gene

Basic Information
Gene ID	3875
Name	KRT18
Synonymous	keratin 18, type I;KRT18;keratin 18, type I
Definition	CK-18\|cell proliferation-inducing gene 46 protein\|cell proliferation-inducing protein 46\|cytokeratin 18\|cytokeratin-18\|keratin, type I cytoskeletal 18\|keratin-18
Position	12q13
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
DEDD(h) + Keratin-18(h) <==> DEDD(h):Keratin-18(h) (binding)
Keratin-18(h) --Caspase-3(h)--> Keratin-18-p26(h) + Keratin-18-p19(h) + protein remnants (processing)
PP2Cbeta(h) + Keratin-18(h) <==> PP2Cbeta(h):Keratin-18(h) (binding)
TNA(h) + Keratin-18(h) <==> TNA(h):Keratin-18(h) (binding)
MCC1(h) + Keratin-18(h) <==> MCC1(h):Keratin-18(h) (binding)
Keratin-18(h) + ATP --> Keratin-18(h){p} + ADP (phosphorylation)
Keratin-18(h) + n ATP --> Keratin-18(h){p}n + n ADP (phosphorylation)
Keratin-15(h) + Keratin-18(h) <==> Keratin-15(h):Keratin-18(h) (binding)
Keratin-18(h) + HRS(h) <==> Keratin-18(h):HRS(h) (binding)
Keratin-18(h) + DIPA(h) <==> Keratin-18(h):DIPA(h) (binding)
Keratin-18(h) + BCUR1(h) <==> Keratin-18(h):BCUR1(h) (binding)
Keratin-18(h) + GCP-4(h) <==> Keratin-18(h):GCP-4(h) (binding)
Keratin-18(h) + nucleoside diphosphate kinase 7(h) <==> Keratin-18(h):nucleoside diphosphate kinase 7(h) (binding)
Keratin-18(h) + exoc8(h) <==> Keratin-18(h):exoc8(h) (binding)
bbs1(h) + Keratin-18(h) <==> bbs1(h):Keratin-18(h) (binding)
bbs2(h) + Keratin-18(h) <==> bbs2(h):Keratin-18(h) (binding)
bbs4(h) + Keratin-18(h) <==> bbs4(h):Keratin-18(h) (binding)
bbs7(h) + Keratin-18(h) <==> bbs7(h):Keratin-18(h) (binding)
Keratin-18(h) + Keratin-8(h) <==> Keratin-18(h):Keratin-8(h) (binding)
KRT18(h) --> Keratin-18(h) (expression).
Keratin-18(h) + Pinin(h) <==> Keratin-18(h):Pinin(h) (binding)
KRT18(h) --> Keratin-18(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
2	N-acetylserine.		Swiss-Prot 53.0
7	Phosphoserine (By similarity).		Swiss-Prot 53.0
8	Phosphothreonine (By similarity).		Swiss-Prot 53.0
11	Phosphothreonine (By similarity).		Swiss-Prot 53.0
18	Phosphoserine (By similarity).		Swiss-Prot 53.0
30	Phosphoserine (By similarity).		Swiss-Prot 53.0
31	Phosphoserine (By similarity).		Swiss-Prot 53.0
34	Phosphoserine; by CDC2.		Swiss-Prot 53.0
36	Phosphotyrosine (By similarity).		Swiss-Prot 53.0
42	Phosphoserine (By similarity).		Swiss-Prot 53.0
53	Phosphoserine; by CAMK, PKC/PRKCE andSTK6.		Swiss-Prot 53.0
52	Phosphoserine (PKC epsilon;)	7523419;1374067	Phospho.ELM 6.0
33	Phosphoserine (CDK1)	9524113;16083285	Phospho.ELM 6.0
6	Phosphoserine	16083285	Phospho.ELM 6.0

Transcription Factors [Top]