| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3589 |
Name | IL11 |
Synonymous | interleukin 11;IL11;interleukin 11 |
Definition | adipogenesis inhibitory factor|interleukin-11|oprelvekin |
Position | 19q13.3-q13.4 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | IL-11(h) + MAGE11(h) <==> IL-11(h):MAGE11(h) (binding) | IL11(h) --> IL-11(h) (expression). | IL-1alpha(h) --> IL-11(h) (increase of secretion) | IL-1beta(h) --> IL-11(h) (increase of secretion) | TGFbeta1(h) --> IL-11(h) (increase of secretion) | TGFbeta2(h) --> IL-11(h) (increase of secretion) | TNF-alpha(h) --> IL-11(h) (increase of secretion) | IL-11(h) --> Ras(m):Raf(m.s.) (increase of binding) | IL-11(h) --> Fyn(m){pY} (increase of phosphorylation) | IL-11(h) --> Grb-2(m):Fyn(m){pY} (increase of binding) | IL-11(h) --> Jak2(m){pY} (increase of phosphorylation) | IL-11(h) --> Grb-2(m):Jak2(m){pY} (increase of binding) | IL-11(h) --> Fyn(m):Jak2(m){pY} (increase of binding) | IL-11(h) --> gp130(m):Jak2(m) (increase of binding) | IL-11(h) --> Cdh5(m) (transactivation) | IL-11(h) --> Pecam1(m) (transactivation) | IL-11(h) --> Kdr(m) (transactivation) | IL-11(h) --> STAT3(m){p} (increase of phosphorylation) | IL11(h) --> IL-11(h) (expression). |
|---|
Post Translational Modification [Top] | |||
There is no record for IL11 | |||
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr19 |
Promoter: 60573126 - 60575126 | GoldenGate_Methylation_Cancer_Panel_I |
chr19 |
Promoter: 60573126 - 60575126 | GSE27584 |
chr19 |
Promoter: 60573126 - 60575126 | Agilent_014791_44K |