Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

330

Name

BIRC3

Synonymous

baculoviral IAP repeat containing 3;BIRC3;baculoviral IAP repeat containing 3

Definition

IAP homolog C|IAP-1|RING finger protein 49|TNFR2-TRAF signaling complex protein|TNFR2-TRAF-signaling complex protein 1|apoptosis inhibitor 2|baculoviral IAP repeat-containing 3|baculoviral IAP repeat-containing protein 3|inhibitor of apoptosis protein 1|m

Position

11q22

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

Smac(h) + cIAP-2(h) <==> Smac(h):cIAP-2(h) (binding)
Smac(m) + cIAP-2(h) <==> Smac(m):cIAP-2(h) (binding)
cIAP-2(h) + n ubiquitin(h) --> cIAP-2(h){ub(n)} (ubiquitination)
cIAP-2(h) + n ubiquitin(v.s.) --E1(rb),Ubc5A(h)--> cIAP-2(h){ub(n)} (ubiquitination)
cIAP-2(h) + n ubiquitin(v.s.) --E1(rb),UbcH6(h)--> cIAP-2(h){ub(n)} (ubiquitination)
cIAP-2(h) --Omi(h)--> protein remnants (processing)
proCaspase-7(h) + cIAP-2(h) <==> proCaspase-7(h):cIAP-2(h) (binding)
proCaspase-9(h) + cIAP-2(h) <==> proCaspase-9(h):cIAP-2(h) (binding)
cIAP-2(h) --> protein remnants (degradation)
BIRC3(h) --> cIAP-2(h) (expression).
IL-3(m.s.) --> cIAP-2(h) (increase of abundance)
IL-5(m.s.) --> cIAP-2(h) (increase of abundance)
cIAP-2(h) + Caspase-9(h) <==> cIAP-2(h):Caspase-9(h) (binding)
cIAP-2(h) --Omi(h)--> protein remnants (cleavage)
BIRC3(h) --> cIAP-2(h) (expression).

Post Translational Modification   [Top]

There is no record for BIRC3

Methylation Profile   [Top]

Chromosome

Location

Source

chr11

Promoter: 101691904 - 101693904Agilent_014791

chr11

Promoter: 101691904 - 101693904GSE27584

chr11

Promoter: 101691904 - 101693904GSE27584

chr11

Promoter: 101691904 - 101693904Agilent_014791_44K

chr11

Promoter: 101691904 - 101693904Agilent_014791_44K