Entrez Gene

Basic Information
Gene ID	329
Name	BIRC2
Synonymous	baculoviral IAP repeat containing 2;BIRC2;baculoviral IAP repeat containing 2
Definition	IAP homolog B\|IAP-2\|NFR2-TRAF signalling complex protein\|RING finger protein 48\|TNFR2-TRAF-signaling complex protein 2\|apoptosis inhibitor 1\|baculoviral IAP repeat-containing 2\|baculoviral IAP repeat-containing protein 2\|inhibitor of apoptosis protein 2
Position	11q22
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
Smac(h) + cIAP-1(h) <==> Smac(h):cIAP-1(h) (binding)
Smac(m) + cIAP-1(h) <==> Smac(m):cIAP-1(h) (binding)
cd40(h) + cIAP-1(h) + TRAF2(h) + TRAF3(h) + TRAF5(h) + TRAF6(h) <==> cd40(h):cd40(h):cd40(h):TRAF2(h):TRAF3(h):TRAF5(h):TRAF6(h):cIAP-1(h) (binding)
cIAP-1(h) + n ubiquitin(h) --> cIAP-1(h){ub(n)} (ubiquitination; automodification)
cIAP-1(h) + n ubiquitin(v.s.) --E1(rb),Ubc5A(h)--> cIAP-1(h){ub(n)} (ubiquitination)
cIAP-1(h) + n ubiquitin(v.s.) --E1(rb),UbcH6(h)--> cIAP-1(h){ub(n)} (ubiquitination)
cIAP-1(h) --Omi(h)--> protein remnants (processing)
CIN85(m.s.) + cIAP-1(h) <==> CIN85(m.s.):cIAP-1(h) (binding)
cIAP-1(h) --> protein remnants (degradation)
cIAP-1(h) + plakoglobin(h) <==> cIAP-1(h):plakoglobin(h) (binding)
cIAP-1(h) + MAGE11(h) <==> cIAP-1(h):MAGE11(h) (binding)
cIAP-1(h) + TRAF2(h) <==> cIAP-1(h):TRAF2(h) (binding)
Birc2(h) --> cIAP-1(h) (expression).
proCaspase-3(v.s.) + n ubiquitin(v.s.) --E1(v.s.),UbcH6(h),cIAP-1(h)--> proCaspase-3(v.s.){ub(n)} (ubiquitination)
proCaspase-9(v.s.) + n ubiquitin(v.s.) --E1(v.s.),UbcH6(h),cIAP-1(h)--> proCaspase-9(v.s.){ub(n)} (ubiquitination)
Caspase-2(h) + cIAP-1(h) <==> Caspase-2(h):cIAP-1(h) (binding)
Caspase-9(h) + cIAP-1(h) <==> Caspase-9(h):cIAP-1(h) (binding)
cIAP-1(h) --Omi(m.s.)--> protein remnants (cleavage)
Birc2(h) --> cIAP-1(h) (expression).

Post Translational Modification [Top]
	There is no record for BIRC2

Transcription Factors [Top]