Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

3075

Name

CFH

Synonymous

complement factor H;CFH;complement factor H

Definition

H factor 1 (complement)|H factor 2 (complement)|adrenomedullin binding protein|age-related maculopathy susceptibility 1|beta-1-H-globulin|beta-1H|factor H|factor H-like 1

Position

1q32

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

CFH(h) --> factor H-isoform1(h) (expression).
beta2-integrin(h) + factor H(h) <==> beta2-integrin(h):factor H(h) (binding)
CD11B(h) + factor H(h) <==> CD11B(h):factor H(h) (binding)
factor H(h) --> lactoferrin(h) (increase of secretion)
complement C3(h) + factor H(h) <==> complement C3(h):factor H(h) (binding)
complement C3(h):BF(m.s.) + factor H(h) <==> complement C3(h):BF(m.s.):factor H(h) (binding)
C4F(h) + factor H(h) <==> C4F(h):factor H(h) (binding)
CO2(h):C4F(h) + factor H(h) <==> CO2(h):C4F(h):factor H(h) (binding)
CFH(h) --> factor H(h) (expression).
CFH(h) --> factor H-isoform 2(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

529N-linked (GlcNAc...).Swiss-Prot 53.0
718N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
802N-linked (GlcNAc...).Swiss-Prot 53.0
822N-linked (GlcNAc...).Swiss-Prot 53.0
882N-linked (GlcNAc...).Swiss-Prot 53.0
911N-linked (GlcNAc...).Swiss-Prot 53.0
1029N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1095N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

There is no record for CFH