Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

29956

Name

CERS2

Synonymous

ceramide synthase 2;CERS2;ceramide synthase 2

Definition

LAG1 homolog, ceramide synthase 2|LAG1 longevity assurance 2|longevity assurance (LAG1, S. cerevisiae) homolog 2|tumor metastasis-suppressor gene 1 protein

Position

1q21.3

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

LASS2(h) --> CerS2(h) (expression).
lignoceroyl-CoA + sphinganine --CerS2(h)--> ceramide + CoA
Necdin(h) + CerS2(h) <==> Necdin(h):CerS2(h) (binding)
LASS2(h) --> CerS2(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

19N-linked (GlcNAc...).Swiss-Prot 53.0
341Phosphoserine.Swiss-Prot 53.0
346Phosphothreonine.Swiss-Prot 53.0
348Phosphoserine.Swiss-Prot 53.0
349Phosphoserine.Swiss-Prot 53.0

Methylation Profile   [Top]

There is no record for CERS2