| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 29028 |
Name | ATAD2 |
Synonymous | ATPase family, AAA domain containing 2;ATAD2;ATPase family, AAA domain containing 2 |
Definition | AAA nuclear coregulator cancer-associated protein|ATPase family AAA domain-containing protein 2 |
Position | 8q24.13 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | ATAD2(h) --> atad2(h) (expression). | atad2(h) --> IGF1R(h) (transactivation) | atad2(h) --> IRS2(h) (transactivation) | atad2(h) --> SGK1(h) (transactivation) | atad2(h) --> BIRC5(h) (transactivation) | atad2(h) --> E2F1(h) (transactivation) | atad2(h) --> CCNA2(h) (transactivation) | atad2(h) --> CCND3(h) (transactivation) | atad2(h) --> IRS-2(h) (increase of abundance) | atad2(h) --> IGF-1R(h) (increase of abundance) | atad2(h) --> SGK-1(h) (increase of abundance) | atad2(h) --> cyclinA2(h) (increase of abundance) | atad2(h) --> cyclinD3(h) (increase of abundance) | atad2(h) --> E2F-1(h) (increase of abundance) | AR(h) + atad2(h) <==> AR(h):atad2(h) (binding) | atad2(h) --> CCND1(h) (transactivation) | atad2(h) --> c-myc(h) (transactivation) | atad2(h) --> cyclinD1(h) (increase of abundance) | ER-alpha(h) + atad2(h) <==> ER-alpha(h):atad2(h) (binding) | SRC3(h) + atad2(h) <==> SRC3(h):atad2(h) (binding) | SRC3(m.s.) + atad2(h) <==> SRC3(m.s.):atad2(h) (binding) | ER-alpha(m.s.) + atad2(h) <==> ER-alpha(m.s.):atad2(h) (binding) | atad2(h) --> KLK3(h) (transactivation) | ATAD2(h) --> atad2(h) (expression). | 5alphaDHT --> atad2(h) (increase of abundance) | AR(h) --> atad2(h) (increase of abundance) | estradiol --> atad2(h) (increase of abundance) |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 342 | Phosphoserine. | Swiss-Prot 53.0 | 751 | Phosphoserine. | Swiss-Prot 53.0 | 1152 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 1243 | Phosphoserine. | Swiss-Prot 53.0 | 751 | Phosphoserine | 15302935 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr8 |
Promoter: 124477368 - 124479368 | Agilent_014791 |
chr8 |
Promoter: 124477368 - 124479368 | GSE27584 |
chr8 |
Promoter: 124477368 - 124479368 | Agilent_014791_44K |