Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

29028

Name

ATAD2

Synonymous

ATPase family, AAA domain containing 2;ATAD2;ATPase family, AAA domain containing 2

Definition

AAA nuclear coregulator cancer-associated protein|ATPase family AAA domain-containing protein 2

Position

8q24.13

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

ATAD2(h) --> atad2(h) (expression).
atad2(h) --> IGF1R(h) (transactivation)
atad2(h) --> IRS2(h) (transactivation)
atad2(h) --> SGK1(h) (transactivation)
atad2(h) --> BIRC5(h) (transactivation)
atad2(h) --> E2F1(h) (transactivation)
atad2(h) --> CCNA2(h) (transactivation)
atad2(h) --> CCND3(h) (transactivation)
atad2(h) --> IRS-2(h) (increase of abundance)
atad2(h) --> IGF-1R(h) (increase of abundance)
atad2(h) --> SGK-1(h) (increase of abundance)
atad2(h) --> cyclinA2(h) (increase of abundance)
atad2(h) --> cyclinD3(h) (increase of abundance)
atad2(h) --> E2F-1(h) (increase of abundance)
AR(h) + atad2(h) <==> AR(h):atad2(h) (binding)
atad2(h) --> CCND1(h) (transactivation)
atad2(h) --> c-myc(h) (transactivation)
atad2(h) --> cyclinD1(h) (increase of abundance)
ER-alpha(h) + atad2(h) <==> ER-alpha(h):atad2(h) (binding)
SRC3(h) + atad2(h) <==> SRC3(h):atad2(h) (binding)
SRC3(m.s.) + atad2(h) <==> SRC3(m.s.):atad2(h) (binding)
ER-alpha(m.s.) + atad2(h) <==> ER-alpha(m.s.):atad2(h) (binding)
atad2(h) --> KLK3(h) (transactivation)
ATAD2(h) --> atad2(h) (expression).
5alphaDHT --> atad2(h) (increase of abundance)
AR(h) --> atad2(h) (increase of abundance)
estradiol --> atad2(h) (increase of abundance)

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

342Phosphoserine.Swiss-Prot 53.0
751Phosphoserine.Swiss-Prot 53.0
1152Phosphothreonine (By similarity).Swiss-Prot 53.0
1243Phosphoserine.Swiss-Prot 53.0
751Phosphoserine15302935Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr8

Promoter: 124477368 - 124479368Agilent_014791

chr8

Promoter: 124477368 - 124479368GSE27584

chr8

Promoter: 124477368 - 124479368Agilent_014791_44K