| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 27043 |
Name | PELP1 |
Synonymous | proline, glutamate and leucine rich protein 1;PELP1;proline, glutamate and leucine rich protein 1 |
Definition | modulator of non-genomic activity of estrogen receptor|proline and glutamic acid rich nuclear protein|proline-, glutamic acid- and leucine-rich protein 1|transcription factor HMX3 |
Position | 17p13.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | MNAR(h) --> MTA3(h) (DNA binding) | STAT3(h) + MNAR(h) <==> STAT3(h):MNAR(h) (binding) | MNAR(h) --> CCND1(h) (transactivation) | MNAR(h) --> FOS(h) (transactivation) | ER-alpha(h) + MNAR(h) <==> ER-alpha(h):MNAR(h) (binding) | ER-beta(h) + MNAR(h) <==> ER-beta(h):MNAR(h) (binding) | MNAR(h) + ER-beta(m.s.) <==> MNAR(h):ER-beta(m.s.) (binding) | Slim-3(h) + MNAR(h) <==> Slim-3(h):MNAR(h) (binding) | MNAR(h) + AR(h) <==> MNAR(h):AR(h) (binding) | pRb(h) + MNAR(h) <==> pRb(h):MNAR(h) (binding) | MNAR(h) + HRS-isoform1(h) <==> MNAR(h):HRS-isoform1(h) (binding) | PELP1(h) --> MNAR(h) (expression). | pRb(m.s.) + MNAR-isoform1(h) <==> pRb(m.s.):MNAR-isoform1(h) (binding) | ER-alpha(h) + MNAR-isoform1(h) <==> ER-alpha(h):MNAR-isoform1(h) (binding) | CBP(h) + MNAR-isoform1(h) <==> CBP(h):MNAR-isoform1(h) (binding) | MNAR-isoform1(h) + p300(h) <==> MNAR-isoform1(h):p300(h) (binding) | PELP1(h) --> MNAR-isoform1(h) (expression). | ER-alpha(m.s.) + MNAR-isoform2(h) <==> ER-alpha(m.s.):MNAR-isoform2(h) (binding) | ER-beta(m.s.) + MNAR-isoform2(h) <==> ER-beta(m.s.):MNAR-isoform2(h) (binding) | AR(m.s.) + MNAR-isoform2(h) <==> AR(m.s.):MNAR-isoform2(h) (binding) | GR(m.s.) + MNAR-isoform2(h) <==> GR(m.s.):MNAR-isoform2(h) (binding) | MNAR-isoform2(h) + ER-alpha(m.s.) + Lck(m.s.) <==> MNAR-isoform2(h):ER-alpha(m.s.):Lck(m.s.) (binding) | Src(h) + MNAR-isoform2(h) <==> Src(h):MNAR-isoform2(h) (binding) | MNAR-isoform2(h) + Src(m.s.) + ER-alpha(m.s.) <==> MNAR-isoform2(h):Src(m.s.):ER-alpha(m.s.) (binding) | ER-alpha(h) + MNAR-isoform2(h) <==> ER-alpha(h):MNAR-isoform2(h) (binding) | MNAR-isoform2(h) --> ERK1(h){p} (increase of phosphorylation) | MNAR-isoform2(h) --> ERK2(h){p} (increase of phosphorylation) | AR(h) + Src(h) + MNAR-isoform2(h) <==> AR(h):Src(h):MNAR-isoform2(h) (binding) | MNAR-isoform2(h) + HRS(m.s.) <==> MNAR-isoform2(h):HRS(m.s.) (binding) | HRS(h) + MNAR-isoform2(h) <==> HRS(h):MNAR-isoform2(h) (binding) | PELP1(h) --> MNAR-isoform2(h) (expression). |
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Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 481 | Phosphoserine. | Swiss-Prot 53.0 | 745 | Phosphothreonine. | Swiss-Prot 53.0 | 1043 | Phosphoserine. | Swiss-Prot 53.0 | 745 | Phosphothreonine | 15302935;17081983 | Phospho.ELM 6.0 | 477 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 481 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 485 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 492 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 749 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
There is no record for PELP1 | ||