| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 253260 |
Name | RICTOR |
Synonymous | RPTOR independent companion of MTOR, complex 2;RICTOR;RPTOR independent companion of MTOR, complex 2 |
Definition | AVO3 homolog|TORC2-specific protein AVO3|pianissimo|rapamycin-insensitive companion of mTOR |
Position | 5p13.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | mTOR(h) + rictor(h) <==> mTOR(h):rictor(h) (binding) | mLST8(h) + mTOR(h) + rictor(h) <==> mLST8(h):mTOR(h):rictor(h) (binding) | rictor(h) + ATP --> rictor(h){p} + ADP (phosphorylation) | SIN1(h) + rictor(h) + mTOR(h) <==> SIN1(h):rictor(h):mTOR(h) (binding) | SIN1(h) + rictor(h) <==> SIN1(h):rictor(h) (binding) | mTOR(h) + Protor-1(h) + rictor(h) <==> mTOR(h):Protor-1(h):rictor(h) (binding) | Protor-1(h) + rictor(h) <==> Protor-1(h):rictor(h) (binding) | Protor-1-isoform1(h) + rictor(h) <==> Protor-1-isoform1(h):rictor(h) (binding) | Protor-1-isoform3(h) + rictor(h) <==> rictor(h):Protor-1-isoform3(h) (binding) | SIN1-isoform1(h) + rictor(h) <==> SIN1-isoform1(h):rictor(h) (binding) | rictor(h) --> AKT(h){pS473} (increase of phosphorylation) | 14-3-3sigma(m.s.) + rictor(h) <==> 14-3-3sigma(m.s.):rictor(h) (binding) | rictor(h) --> PKCalpha(m.s.){p} (increase of phosphorylation) | rictor(h) --> PKCalpha(h){p} (increase of phosphorylation) | mTOR(h) + rictor(h) + mLST8(h) + SIN1(h) + Protor-1(h) <==> mTOR(h):rictor(h):mLST8(h):SIN1(h):Protor-1(h) (binding) | RICTOR(h) --> rictor(h) (expression). | rictor(h){p} --> rictor(h) + ADP (dephosphorylation) | AKT-1(m.s.) + ATP --rictor(h)--> AKT-1(m.s.){p} + ADP (phosphorylation) | RICTOR(h) --> rictor(h) (expression). |
|---|
Post Translational Modification [Top] | |||
There is no record for RICTOR | |||
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr5 |
Promoter: 39109758 - 39111758 | Agilent_014791 |
chr5 |
Promoter: 39109758 - 39111758 | GSE27584 |
chr5 |
Promoter: 39109758 - 39111758 | Agilent_014791_44K |
chr5 |
Promoter: 39109758 - 39111758 | Agilent_014791 |