Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

253260

Name

RICTOR

Synonymous

RPTOR independent companion of MTOR, complex 2;RICTOR;RPTOR independent companion of MTOR, complex 2

Definition

AVO3 homolog|TORC2-specific protein AVO3|pianissimo|rapamycin-insensitive companion of mTOR

Position

5p13.1

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

mTOR(h) + rictor(h) <==> mTOR(h):rictor(h) (binding)
mLST8(h) + mTOR(h) + rictor(h) <==> mLST8(h):mTOR(h):rictor(h) (binding)
rictor(h) + ATP --> rictor(h){p} + ADP (phosphorylation)
SIN1(h) + rictor(h) + mTOR(h) <==> SIN1(h):rictor(h):mTOR(h) (binding)
SIN1(h) + rictor(h) <==> SIN1(h):rictor(h) (binding)
mTOR(h) + Protor-1(h) + rictor(h) <==> mTOR(h):Protor-1(h):rictor(h) (binding)
Protor-1(h) + rictor(h) <==> Protor-1(h):rictor(h) (binding)
Protor-1-isoform1(h) + rictor(h) <==> Protor-1-isoform1(h):rictor(h) (binding)
Protor-1-isoform3(h) + rictor(h) <==> rictor(h):Protor-1-isoform3(h) (binding)
SIN1-isoform1(h) + rictor(h) <==> SIN1-isoform1(h):rictor(h) (binding)
rictor(h) --> AKT(h){pS473} (increase of phosphorylation)
14-3-3sigma(m.s.) + rictor(h) <==> 14-3-3sigma(m.s.):rictor(h) (binding)
rictor(h) --> PKCalpha(m.s.){p} (increase of phosphorylation)
rictor(h) --> PKCalpha(h){p} (increase of phosphorylation)
mTOR(h) + rictor(h) + mLST8(h) + SIN1(h) + Protor-1(h) <==> mTOR(h):rictor(h):mLST8(h):SIN1(h):Protor-1(h) (binding)
RICTOR(h) --> rictor(h) (expression).
rictor(h){p} --> rictor(h) + ADP (dephosphorylation)
AKT-1(m.s.) + ATP --rictor(h)--> AKT-1(m.s.){p} + ADP (phosphorylation)
RICTOR(h) --> rictor(h) (expression).

Post Translational Modification   [Top]

There is no record for RICTOR

Methylation Profile   [Top]

Chromosome

Location

Source

chr5

Promoter: 39109758 - 39111758Agilent_014791

chr5

Promoter: 39109758 - 39111758GSE27584

chr5

Promoter: 39109758 - 39111758Agilent_014791_44K

chr5

Promoter: 39109758 - 39111758Agilent_014791