| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2494 |
Name | NR5A2 |
Synonymous | nuclear receptor subfamily 5, group A, member 2;NR5A2;nuclear receptor subfamily 5, group A, member 2 |
Definition | CYP7A promoter-binding factor|alpha-1-fetoprotein transcription factor|b1-binding factor, hepatocyte transcription factor which activates enhancer II of hepatitis B virus|fetoprotein-alpha 1 (AFP) transcription factor|hepatocytic transcription factor hB1F |
Position | 1q32.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | SHP(h) + LRH-1(h) <==> SHP(h):LRH-1(h) (binding). | GATA-4(r) + LRH-1(h) <==> GATA-4(r):LRH-1(h) (binding) | GATA-6(r) + LRH-1(h) <==> GATA-6(r):LRH-1(h) (binding) | LRH-1(h) + MBF-1alpha(h) <==> LRH-1(h):MBF-1alpha(h) (binding) | LRH-1(h) + sumo1(h) --> LRH-1(h){sumo} (sumoylation) | LRH-1(h) --> HBV enhancer(HBV) (DNA binding). | LRH-1(h) + SHP(m) <==> LRH-1(h):SHP(m) (binding) | LRH-1(h) --/ CYP7A1(h) (transrepression) | LRH-1(h) --/ NR0B2(h) (transrepression) | LRH-1(h) --> ABCC3(h) (DNA binding). | LRH-1(h) --> CYP19A1(h) (DNA binding). | LRH-1(h) + prox1(h) <==> LRH-1(h):prox1(h) (binding) | SRC-1(h) + LRH-1(h) <==> SRC-1(h):LRH-1(h) (binding) | PNRC(h) + LRH-1(h) <==> PNRC(h):LRH-1(h) (binding) | LRH-1(h) + PNRC2(h) <==> LRH-1(h):PNRC2(h) (binding) | RIP140(h) + LRH-1(h) <==> RIP140(h):LRH-1(h) (binding) | LRH-1(h) + ICEN22(h) <==> LRH-1(h):ICEN22(h) (binding) | LRH-1(h) --> HMGCR(HA) (DNA binding; transactivation). | LRH-1(h) --> STAR(h) (DNA binding). | LRH-1(h) --> CYP11A1(h) (DNA binding). | LRH-1(h) --> HSD3B2(h) (transactivation) | LRH-1(h) --> SCARB1(h) (transactivation) | LRH-1(h) --> apoAI(h) (DNA binding; transactivation). | LRH-1(h) --> NR0B2(m) (DNA binding; transactivation). | LRH-1(h) --> APOM(h) (DNA binding; transactivation). | LRH-1(h) --> Abcg5(h) (DNA binding; transactivation). | LRH-1(h) --> ABCG8(h) (DNA binding; transactivation). | LRH-1(h) --> Slc10a2(m) (DNA binding). | NR5A2(h) --> LRH-1(h) (expression). | LRH-1-xbb1(h) --> CYP7A1(h) (DNA binding; transregulation). | LRH-1-xbb1(h) --> CYP8B1(r) (DNA binding; transactivation). | LRH-1-xbb1(h) --/ CYP7A1(rb) (DNA binding; transrepression). | NR5A2(h) --> LRH-1-xbb1(h) (expression). | LRH1-isoform1(h) + SRC-1A(h) <==> LRH1-isoform1(h):SRC-1A(h) (binding) | LRH1-isoform1(h) --> CYP7A1(h) (transactivation) | LRH1-isoform1(h) + TIF2(h) <==> LRH1-isoform1(h):TIF2(h) (binding) | LRH1-isoform1(h) + SRC3-xbb1(h) <==> LRH1-isoform1(h):SRC3-xbb1(h) (binding) | LRH1-isoform1(h) --> ADIPOQ(h) (DNA binding; transactivation). | LRH1-isoform1(h) + sumo1(m.s.) --> LRH1-isoform1(h){sumo} (sumoylation) | LRH1-isoform1(h) + sumo1(m.s.) --Aos1(m.s.):SAE2(m.s.),Ubc9(m.s.),PIAS2-alpha(m.s.)--> LRH1-isoform1(h){sumoK224} (sumoylation) | LRH1-isoform1(h) + sumo1(m.s.) --Aos1(m.s.):SAE2(m.s.),Ubc9(m.s.),PIAS1(m.s.)--> LRH1-isoform1(h){sumo} (sumoylation) | LRH1-isoform1(h) --> AFP(r) (DNA binding; transregulation). | LRH1-isoform1(h) --> Cyp11b1(m) (DNA binding). | LRH1-isoform1(h) --> Cyp7a1(r) (DNA binding; transactivation). | NR5A2(h) --> LRH1-isoform1(h) (expression). | NR5A2(h) --> LRH1-isoform2(h) (expression). | NR5A2(h) --> LRH1-isoform3(h) (expression). |
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Post Translational Modification [Top] | |||
There is no record for NR5A2 | |||
Methylation Profile [Top] | ||
There is no record for NR5A2 | ||