| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 23451 |
Name | SF3B1 |
Synonymous | splicing factor 3b, subunit 1, 155kDa;SF3B1;splicing factor 3b, subunit 1, 155kDa |
Definition | SAP 155|pre-mRNA processing 10|pre-mRNA splicing factor SF3b, 155 kDa subunit|spliceosome-associated protein 155|splicing factor 3B subunit 1|splicing factor 3b, subunit 1, 155kD |
Position | 2q33.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | SF3B1(h) --> SF3b1(h) (expression). | SF3b1(h) + calmodulin(b) <==> SF3b1(h):calmodulin(b) (binding) | SPF30(h) + SF3b1(h) <==> SPF30(h):SF3b1(h) (binding) | rnps1(h) + SF3b1(h) <==> rnps1(h):SF3b1(h) (binding) | SIAHBP1(h) + SF3b1(h) <==> SIAHBP1(h):SF3b1(h) (binding) | SN-URF(h) + SF3b1(h) <==> SN-URF(h):SF3b1(h) (binding) | APG12(h) + SF3b1(h) <==> APG12(h):SF3b1(h) (binding) | SPF38(h) + SF3b1(h) <==> SPF38(h):SF3b1(h) (binding) | GSK3beta(h) + SF3b1(h) <==> GSK3beta(h):SF3b1(h) (binding) | BRF-2(h) + SF3b1(h) <==> BRF-2(h):SF3b1(h) (binding) | HDAC3(h) + SF3b1(h) <==> HDAC3(h):SF3b1(h) (binding) | 14-3-3zeta(h) + SF3b1(h) <==> 14-3-3zeta(h):SF3b1(h) (binding) | SF3b1(h) + CAPER-alpha(h) <==> SF3b1(h):CAPER-alpha(h) (binding) | SF3B1(h) --> SF3b1(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 142 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 207 | Phosphothreonine. | Swiss-Prot 53.0 | 211 | Phosphothreonine. | Swiss-Prot 53.0 | 223 | Phosphothreonine. | Swiss-Prot 53.0 | 227 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 244 | Phosphothreonine (Probable). | Swiss-Prot 53.0 | 248 | Phosphothreonine (Probable). | Swiss-Prot 53.0 | 267 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 296 | Phosphothreonine. | Swiss-Prot 53.0 | 299 | Phosphothreonine. | Swiss-Prot 53.0 | 313 | Phosphothreonine (Probable). | Swiss-Prot 53.0 | 316 | Phosphothreonine. | Swiss-Prot 53.0 | 326 | Phosphothreonine. | Swiss-Prot 53.0 | 328 | Phosphothreonine. | Swiss-Prot 53.0 | 344 | Phosphoserine. | Swiss-Prot 53.0 | 350 | Phosphothreonine. | Swiss-Prot 53.0 | 354 | Phosphothreonine. | Swiss-Prot 53.0 | 350 | Phosphothreonine | 15302935 | Phospho.ELM 6.0 | 354 | Phosphothreonine | 15302935 | Phospho.ELM 6.0 | 235 | Phosphothreonine | 16083285 | Phospho.ELM 6.0 | 244 | Phosphothreonine (CDK2) | 12105215;17081983 | Phospho.ELM 6.0 | 248 | Phosphothreonine (CDK2) | 12105215;17081983 | Phospho.ELM 6.0 | 313 | Phosphothreonine (CDK2) | 12105215 | Phospho.ELM 6.0 | 129 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 207 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 211 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 217 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 223 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 227 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 296 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 299 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 303 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 316 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 326 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 344 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 349 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 434 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 436 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr2 |
Promoter: 198007516 - 198009516 | Agilent_014791 |
chr2 |
Promoter: 198007516 - 198009516 | Agilent_014791_44K |
chr2 |
Promoter: 198007516 - 198009516 | Agilent_014791_44K |