| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 23028 |
Name | KDM1A |
Synonymous | lysine (K)-specific demethylase 1A;KDM1A;lysine (K)-specific demethylase 1A |
Definition | BRAF35-HDAC complex protein BHC110|FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit|amine oxidase (flavin containing) domain 2|flavin-containing amine oxidase domain-containing protein 2|lysine (K)-specific demethylase 1|lysine-specific histone de |
Position | 1p36.12 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | LSD1-isoform1(h) + BHC80(h) <==> LSD1-isoform1(h):BHC80(h) (binding) | AOF2(h) --> LSD1-isoform1(h) (expression). | LSD1(h) + HDAC1(h) <==> LSD1(h):HDAC1(h) (binding) | hdac2(h) + LSD1(h) <==> hdac2(h):LSD1(h) (binding) | RCOR1(h) + LSD1(h) + MBD2a(h) + Mi2-alpha(h) + MTA1L1(h) + sin3a(h) + RbAp48(h) + HDAC1(h) <==> RCOR1(h):LSD1(h):MBD2a(h):Mi2-alpha(h):MTA1L1(h):sin3a(h):RbAp48(h):HDAC1(h) (binding) | LSD1(h) + HDAC1(h) <==> LSD1(h):HDAC1(h) (binding) | LSD1(h) --> KLK3(h) (transactivation) | LSD1(h) --> NKX3-1(h) (transactivation) | LSD1(h) --> TMPRSS2(h) (transactivation) | ZABC1(h) + LSD1(h) + RCOR1(h) <==> ZABC1(h):LSD1(h):RCOR1(h) (binding) | RCOR1(h) + HDAC1(h) + sin3a(h) + LSD1(h) <==> RCOR1(h):HDAC1(h):sin3a(h):LSD1(h) (binding) | BRAF35(h) + hdac2(h) + HDAC1(h) + RCOR1(h) + BHC80(h) + LSD1(h) <==> BRAF35(h):hdac2(h):HDAC1(h):RCOR1(h):BHC80(h):LSD1(h) (binding) | BRAF35(m.s.) + hdac2(h) + HDAC1(h) + RCOR1(h) + BHC80(h) + LSD1(h) <==> BRAF35(m.s.):hdac2(h):HDAC1(h):RCOR1(h):BHC80(h):LSD1(h) (binding) | LSD1(h) + RCOR1(h) <==> LSD1(h):RCOR1(h) (binding) | LSD1(h) + GDF9(h) <==> LSD1(h):GDF9(h) (binding) | ascc2(h) + LSD1(h) <==> ascc2(h):LSD1(h) (binding) | AOF2(h) --> LSD1(h) (expression). | histone H3(m.s.){met(2)K5} --LSD1(h)--> histone H3(m.s.) + 2 formaldehyde (demethylation) | histone H3(h){metK5} --LSD1(h)--> histone H3(h) + formaldehyde (demethylation) | histone H3(m.s.){metK5} --LSD1(h)--> histone H3(m.s.) + formaldehyde (demethylation) | AOF2(h) --> LSD1-isoform2(h) (expression). |
|---|
Post Translational Modification [Top] | |||
There is no record for KDM1A | |||
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr1 |
Promoter: 23217033 - 23219033 | GSE27584 |
chr1 |
Promoter: 23217033 - 23219033 | Agilent_014791_44K |