| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2150 |
Name | F2RL1 |
Synonymous | coagulation factor II (thrombin) receptor-like 1;F2RL1;coagulation factor II (thrombin) receptor-like 1 |
Definition | G-protein coupled receptor 11|coagulation factor II receptor-like 1|protease-activated receptor 2|proteinase-activated receptor 2|thrombin receptor-like 1 |
Position | 5q13 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | PAR2(h) + ubiquitin(r) --> PAR2(h){ub} (ubiquitination) | PAR2(h) + ubiquitin(h) --> PAR2(h){ub} (ubiquitination) | PAR2(h) + c-Cbl(r) <==> PAR2(h):c-Cbl(r) (binding) | PAR2(h) --> Cdc42(h) (activation) | PAR2(h) --> IL-8(h) (increase of abundance) | F2RL1(h) --> PAR2(h) (expression). | Dkk-1(h) --/ PAR2(h) (decrease of abundance) | PAR2(h) --> PGE2 (increase of secretion) | PAR2(h) --> prostaglandin F2-alpha (increase of secretion) | F2RL1(h) --> PAR2(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 30 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 222 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr5 |
Promoter: 76149110 - 76151110 | Agilent_014791 |
chr5 |
Promoter: 76149110 - 76151110 | GSE27584 |
chr5 |
Promoter: 76149110 - 76151110 | Agilent_014791_44K |