| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2078 |
Name | ERG |
Synonymous | v-ets avian erythroblastosis virus E26 oncogene homolog;ERG;v-ets avian erythroblastosis virus E26 oncogene homolog |
Definition | TMPRSS2/ERG fusion|ets-related|transcriptional regulator ERG|transcriptional regulator ERG (transforming protein ERG)|v-ets avian erythroblastosis virus E26 oncogene related|v-ets erythroblastosis virus E26 oncogene homolog|v-ets erythroblastosis virus E2 |
Position | 21q22.3 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | Erg-1(h) --> NOS3(h) (DNA binding; transactivation). | ERG(h) --> Erg-1(h) (expression). | ERG(h) --> Erg-2(h) (expression). | p38erg(h) --> MSV(MSV) (DNA binding). | p38erg(h) --> Py(PA) (DNA binding). | ERG(h) --> p38erg(h) (expression). | p55erg(h) --> MSV(MSV) (DNA binding). | p55erg(h) --> Py(PA) (DNA binding). | ERG(h) --> p55erg(h) (expression). | p49erg(h) --> MSV(MSV) (DNA binding). | p49erg(h) --> Py(PA) (DNA binding). | ERG(h) --> p49erg(h) (expression). | Erg(h) + c-Ets-2(h) <==> Erg(h):c-Ets-2(h) (binding) [re. | ERG(h) --> Erg(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 93 | Phosphoserine. | Swiss-Prot 53.0 | 85 | Phosphoserine | 15302935 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr21 |
Promoter: 38954988 - 38956988 | Agilent_014791 |
chr21 |
Promoter: 38954988 - 38956988 | GoldenGate_Methylation_Cancer_Panel_I |
chr21 |
Promoter: 38791767 - 38793767 | GSE27584 |
chr21 |
Promoter: 38954988 - 38956988 | GSE27584 |
chr21 |
Promoter: 38954988 - 38956988 | Agilent_014791_44K |