| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2056 |
Name | EPO |
Synonymous | erythropoietin;EPO;erythropoietin |
Definition | epoetin |
Position | 7q22 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | Epo(h) + EpoR(h) <==> Epo(h):EpoR(h) (binding) | Epo(h) + 2 EpoR(h) <==> Epo(h):(EpoR(h))2 (binding) | Epo(h) --> Epo(h) (expression). | Epo(h) --> AKT(m){pT308} (increase of phosphorylation) | Epo(h) --> PLCgamma2(m){pY} (increase of phosphorylation) | Epo(h) --> STAT3(m):STAT3(m) (increase of binding) | Epo(h) --> SHP-2(h){pY} (increase of phosphorylation) | Epo(h) --> Epo(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 153 | O-linked (GalNAc...). | Swiss-Prot 53.0 | 153 | O-linked | Takeuchi, M. and Kobata, A. (1991) Glycobiology, 1, 337-346. | OGlycBase6.0 | 51 | N-liked | Takeuchi, M. and Kobata, A. (1991) Glycobiology, 1, 337-346. | OGlycBase6.0 | 65 | N-liked | Takeuchi, M. and Kobata, A. (1991) Glycobiology, 1, 337-346. | OGlycBase6.0 | 110 | N-liked | Takeuchi, M. and Kobata, A. (1991) Glycobiology, 1, 337-346. | OGlycBase6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr7 |
Promoter: 100154859 - 100156859 | Agilent_014791 |
chr7 |
Promoter: 100154859 - 100156859 | GoldenGate_Methylation_Cancer_Panel_I |
chr7 |
Promoter: 100154859 - 100156859 | GSE27584 |