Entrez Gene

Basic Information
Gene ID	2023
Name	ENO1
Synonymous	enolase 1, (alpha);ENO1;enolase 1, (alpha)
Definition	2-phospho-D-glycerate hydro-lyase\|MYC promoter-binding protein 1\|alpha enolase like 1\|alpha-enolase\|enolase-alpha\|non-neural enolase\|phosphopyruvate hydratase\|plasminogen-binding protein\|tau-crystallin
Position	1p36.2
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
alpha-enolase(h) --> c-myc(h) (DNA binding).
alpha-enolase(h) --/ MKK5-isoform2(h) (decrease of abundance)
alpha-enolase(h) --> ERK5(h){p} (decrease of phosphorylation)
alpha-enolase(h) --> HSD3B1(h) (DNA binding).
alpha-enolase(h) --> HSD3B2(h) (DNA binding; transactivation).
ENO1(h) --> alpha-enolase(h) (expression).
MKK5(r) + alpha-enolase-isoform2(h) <==> MKK5(r):alpha-enolase-isoform2(h) (binding)
NICD1(h) + alpha-enolase-isoform2(h) <==> NICD1(h):alpha-enolase-isoform2(h) (binding)
NICD1(h) + alpha-enolase-isoform2(h) <==> NICD1(h):alpha-enolase-isoform2(h) (binding)
NICD1(h) + YY1(h) + alpha-enolase-isoform2(h) <==> NICD1(h):YY1(h):alpha-enolase-isoform2(h) (binding)
alpha-enolase-isoform2(h) --/ c-myc(h) (transrepression)
ENO1(h) --> alpha-enolase-isoform2(h) (expression).
NICD1(h) + alpha-enolase(h) <==> NICD1(h):alpha-enolase(h) (binding)
NICD1(h) + alpha-enolase(h) <==> NICD1(h):alpha-enolase(h) (binding)
NICD1(h) + YY1(h) + alpha-enolase(h) <==> NICD1(h):YY1(h):alpha-enolase(h) (binding)
alpha-enolase(h) --/ c-myc(h) (transrepression)
ENO1(h) --> alpha-enolase(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
44	Phosphotyrosine.		Swiss-Prot 53.0
71	N6-acetyllysine.		Swiss-Prot 53.0
263	Phosphoserine (By similarity).		Swiss-Prot 53.0
287	Phosphotyrosine.		Swiss-Prot 53.0
43	Phosphotyrosine (Src)	96108162;15592455	Phospho.ELM 6.0
286	Phosphotyrosine	15592455	Phospho.ELM 6.0

Transcription Factors [Top]