| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1977 |
Name | EIF4E |
Synonymous | eukaryotic translation initiation factor 4E;EIF4E;eukaryotic translation initiation factor 4E |
Definition | eIF-4E|eIF-4F 25 kDa subunit|eukaryotic translation initiation factor 4E-like 1|mRNA cap-binding protein |
Position | 4q23 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | 4E-BP1(h) + eIF-4E(h) <==> 4E-BP1(h):eIF-4E(h) (binding) | 4E-BP3(h) + eIF-4E(h) <==> 4E-BP3(h):eIF-4E(h) (binding) | eIF-4E(h) + 4E-BP2(m) <==> eIF-4E(h):4E-BP2(m) (binding) | eIF-4E(h) + 4E-BP1(r) <==> eIF-4E(h):4E-BP1(r) (binding) | eIF-4GI(h) + eIF-4E(h) + eIF-4A(h) <==> eIF-4GI(h):eIF-4E(h):eIF-4A(h) (binding) | eIF-4GII(h) + eIF-4A(h) + eIF-4E(h) <==> eIF-4GII(h):eIF-4A(h):eIF-4E(h) (binding) | eIF-4E(h) + PML(h) <==> eIF-4E(h):PML(h) (binding) | eIF-4E(h) + ATP --> eIF-4E(h){pS} + ADP (phosphorylation) | Hex(h) + eIF-4E(h) <==> Hex(h):eIF-4E(h) (binding) | Hex(m.s.) + eIF-4E(h) <==> Hex(m.s.):eIF-4E(h) (binding) | hoxa9(h) + eIF-4E(h) <==> hoxa9(h):eIF-4E(h) (binding) | EIF4A2(h) + eIF-4E(h) <==> EIF4A2(h):eIF-4E(h) (binding) | eIF-4AI(h) + eIF-4E(h) <==> eIF-4AI(h):eIF-4E(h) (binding) | eIF-4E(h) + ATP --> eIF-4E(h){p} + ADP (phosphorylation) | eIF-4E(h) + ATP --> eIF-4E(h){pS209} + ADP (phosphorylation) | EIF4E(h) --> eIF-4E(h) (expression). | EIF4E(h) --> eIF-4E(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 209 | Phosphoserine (by PKC). | Swiss-Prot 53.0 | 209 | Phosphoserine (Mnk1;Mnk2) | 95301551;11463832;11723111 | Phospho.ELM 6.0 | 53 | Phosphoserine | 87280093 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
There is no record for EIF4E | ||