| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1874 |
Name | E2F4 |
Synonymous | E2F transcription factor 4, p107/p130-binding;E2F4;E2F transcription factor 4, p107/p130-binding |
Definition | p107/p130-binding protein|transcription factor E2F4 |
Position | 16q22.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | E2F-4(h) + p107(h) <==> E2F-4(h):p107(h) (binding) | E2F-4(h) --> CDC2(h) (DNA binding). | E2F-4(h) --> PCNA(h) (DNA binding). | E2F-4(h) --> B-myb(m) (DNA binding). | E2F-4(h) + DP-1(h) <==> E2F-4(h):DP-1(h) (binding) | E2F-4(h) + pRb(h) <==> E2F-4(h):pRb(h) (binding) | E2F-4(h) + p130(h) <==> E2F-4(h):p130(h) (binding) | E2F-4(h) + p130(h) + cyclinA(h):Cdk2(h) <==> E2F-4(h):p130(h):cyclinA(h):Cdk2(h) (binding) | DP-1(m) + E2F-4(h) <==> DP-1(m):E2F-4(h) (binding). | DP-2(h) + E2F-4(h) <==> DP-2(h):E2F-4(h) (binding). | HDAC1(h) + p130(h) + E2F-4(h) <==> HDAC1(h):p130(h):E2F-4(h) (binding) | E2F-4(h) + brca1(h) <==> E2F-4(h):brca1(h) (binding) | E2F-4(h) --/ DIRAS3(h) (DNA binding; transrepression). | E2F-4(h) --> Tuba3b(m) (DNA binding). | E2F-4(h) + ATP --> E2F-4(h){p} + ADP (phosphorylation) | E2F-4(h) --> DHFR(ha) (DNA binding). | E2F-4(h) --> POMC(h) (DNA binding). | E2F-4(h) --> AURKB(h) (DNA binding). | E2F4(h) --> E2F-4(h) (expression). | DP-2(h) + E2F-4(h) <==> DP-2(h):E2F-4(h) (binding) | Slim-3(h) + E2F-4(h) <==> Slim-3(h):E2F-4(h) (binding) | E2F-4(h) + DEDAF(h) <==> E2F-4(h):DEDAF(h) (binding) | E2F-4(h) + DEDAF(h) <==> E2F-4(h):DEDAF(h) (binding) | E2F-4(h) --/ DIRAS3(h) (transrepression) | E2F-4(h) + 2 ATP --IKK-alpha(m.s.)--> E2F-4(h){pS281}{pS285} + 2 ADP (phosphorylation) | E2F-4(h) + 2 ATP --IKK-beta(m.s.)--> E2F-4(h){pS281}{pS285} + 2 ADP (phosphorylation) | E2F-4(h) + p130(h) <==> E2F-4(h):p130(h) (binding) | E2F-4(h) --> MAP3K5(h) (DNA binding; transactivation). | E2F-4(h) --> MAP3K5(h) (transactivation) | E2F4(h) --> E2F-4(h) (expression). |
|---|
Post Translational Modification [Top] | |||
There is no record for E2F4 | |||
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr16 |
Promoter: 65782069 - 65784069 | GSE27584 |
chr16 |
Promoter: 65782069 - 65784069 | Agilent_014791_44K |
chr16 |
Promoter: 65782069 - 65784069 | Agilent_014791 |