| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1785 |
Name | DNM2 |
Synonymous | dynamin 2;DNM2;dynamin 2 |
Definition | dynamin II|dynamin-2 |
Position | 19p13.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | pde6g(m) + dynamin2(h) <==> pde6g(m):dynamin2(h) (binding) | ErbB2(m.s.) + dynamin2(h) <==> ErbB2(m.s.):dynamin2(h) (binding) | importin-beta1(h) + dynamin2(h) <==> importin-beta1(h):dynamin2(h) (binding) | dynamin2(h) --/ VEGFR-2(h) (decrease of abundance) | dynamin2(h) + IL-5Ralpha(h) <==> dynamin2(h):IL-5Ralpha(h) (binding) | dynamin2(h) + Lyn(h) <==> dynamin2(h):Lyn(h) (binding) | Jak2(h) + dynamin2(h) <==> Jak2(h):dynamin2(h) (binding) | dynamin2(h) + ATP --> dynamin2(h){pY} + ADP (phosphorylation) | dynamin2(h) --/ ERK2(h){pT185}{pY187} (decrease of phosphorylation; inhibition) | dynamin2(h) --/ ERK1(h){pT202}{pY204} (decrease of phosphorylation) | DNM2(h) --> dynamin2(h) (expression). | DNM2(h) --> dynamin2-isoform1(h) (expression). | DNM2(h) --> dynamin2-isoform2(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 766 | Phosphothreonine. | Swiss-Prot 53.0 | 762 | Phosphoserine | 15302935 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr19 |
Promoter: 10688255 - 10690255 | Agilent_014791 |
chr19 |
Promoter: 10688255 - 10690255 | GSE27584 |
chr19 |
Promoter: 10688255 - 10690255 | GSE27584 |
chr19 |
Promoter: 10688255 - 10690255 | GSE27584 |
chr19 |
Promoter: 10688255 - 10690255 | GSE27584 |
chr19 |
Promoter: 10688255 - 10690255 | Agilent_014791_44K |