| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1435 |
Name | CSF1 |
Synonymous | colony stimulating factor 1 (macrophage);CSF1;colony stimulating factor 1 (macrophage) |
Definition | lanimostim|macrophage colony-stimulating factor 1 |
Position | 1p13.3 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | M-CSF(h) --> TLR2(h) (transactivation) | M-CSF(h) --/ TLR5(h) (transrepression) | M-CSF(h) --> TLR4(h) (transactivation) | M-CSF(h) --/ TLR9(h) (transrepression) | M-CSF(h) --> TNF(m) (increase of secretion) | M-CSF(h) --> Tnf(m) (transactivation) | M-CSF(h) --> IL-6(m) (increase of secretion) | M-CSF(h) --> Il6(m) (transactivation) | M-CSF(h) --/ IRAK1(m) (decrease of abundance) | M-CSF(h) --/ IkappaB-alpha(m) (decrease of abundance) | M-CSF(h) --> p38(m){pT}{pY} (increase of phosphorylation) | M-CSF(h) --> JNK(m){pT}{pY} (increase of phosphorylation) | M-CSF(h) --> ERK1(m){pT203} (increase of phosphorylation) | M-CSF(h) --> ERK2(m){pY185} (increase of phosphorylation) | M-CSF(h) --> Tlr9(m) (transactivation) | M-CSF(h) --> M-CSF-1-R(m){pY} (increase of phosphorylation) | M-CSF(h) --> myo18a(m){pY} (increase of phosphorylation) | M-CSF(h) --> gelsolin(m){pY} (increase of phosphorylation) | M-CSF(h) --> GRP58(m){pY} (increase of phosphorylation) | CSF1(h) --> M-CSF(h) (expression). | CSF1(h) --> CSF1_1(h) (expression). | hsa-miR-130a --/ CSF1_1(h) (predicted) | hsa-miR-130b --/ CSF1_1(h) (predicted) | hsa-miR-27a --/ CSF1_1(h) (predicted) | CSF1(h) --> CSF1_2(h) (expression). | CSF1(h) --> CSF1_3(h) (expression). | CSF1(h) --> M-CSF-isoform1(h) (expression). | CSF1(h) --> M-CSF-isoform2(h) (expression). | CSF1(h) --> M-CSF-isoform3(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 154 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 172 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr1 |
Promoter: 110253480 - 110255480 | Agilent_014791 |
chr1 |
Promoter: 110253480 - 110255480 | GoldenGate_Methylation_Cancer_Panel_I |
chr1 |
Promoter: 110253480 - 110255480 | GoldenGate_Methylation_Cancer_Panel_I |
chr1 |
Promoter: 110253480 - 110255480 | GoldenGate_Methylation_Cancer_Panel_I |
chr1 |
Promoter: 110253480 - 110255480 | GoldenGate_Methylation_Cancer_Panel_I |
chr1 |
Promoter: 110253480 - 110255480 | GSE27584 |
chr1 |
Promoter: 110253480 - 110255480 | GSE27584 |
chr1 |
Promoter: 110253480 - 110255480 | GSE27584 |
chr1 |
Promoter: 110253480 - 110255480 | GSE27584 |
chr1 |
Promoter: 110253480 - 110255480 | Agilent_014791_44K |
chr1 |
Promoter: 110253480 - 110255480 | Agilent_014791_44K |
chr1 |
Promoter: 110253480 - 110255480 | Agilent_014791_44K |
chr1 |
Promoter: 110253480 - 110255480 | Agilent_014791_44K |