Entrez Gene

Basic Information
Gene ID	10987
Name	COPS5
Synonymous	COP9 signalosome subunit 5;COPS5;COP9 signalosome subunit 5
Definition	38 kDa Mov34 homolog\|COP9 constitutive photomorphogenic homolog subunit 5\|COP9 signalosome complex subunit 5\|jun activation domain-binding protein 1\|signalosome subunit 5
Position	8q13.1
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
beta2-integrin(h) + JAB1(h) <==> beta2-integrin(h):JAB1(h) (binding)
JAB1(h) + p53(h) <==> JAB1(h):p53(h) (binding)
Trx(h) + JAB1(h) <==> Trx(h):JAB1(h) (binding)
JAB1(h) + p27Kip1(h) <==> JAB1(h):p27Kip1(h) (binding)
ER-alpha(h) + JAB1(h) <==> ER-alpha(h):JAB1(h) (binding)
JAB1(h) + Smad4(m.s.) <==> JAB1(h):Smad4(m.s.) (binding)
JAB1(h) + E2F-1(h) <==> JAB1(h):E2F-1(h) (binding)
SRC-1(h) + JAB1(h) <==> SRC-1(h):JAB1(h) (binding)
PPARgamma(h) + JAB1(h) <==> PPARgamma(h):JAB1(h) (binding)
RORalpha(h) + JAB1(h) <==> RORalpha(h):JAB1(h) (binding)
HNF-4alpha(h) + JAB1(h) <==> HNF-4alpha(h):JAB1(h) (binding)
HNF4gamma(h) + JAB1(h) <==> HNF4gamma(h):JAB1(h) (binding)
Fas(m) + JAB1(h) <==> Fas(m):JAB1(h) (binding)
NURR1(h) + JAB1(h) <==> NURR1(h):JAB1(h) (binding)
NOR1(h) + JAB1(h) <==> NOR1(h):JAB1(h) (binding)
JAB1(h) --> HIF-1alpha(h) (increase of abundance)
JAB1(h) --> HIF2A(h) (increase of abundance)
JAB1(h) --> HIF-1alpha(h):VHL(m.s.) (decrease of binding)
Cops5(h) --> JAB1(h) (expression).
JAB1(h) + E2F-1(h) <==> JAB1(h):E2F-1(h) (binding)
JAB1(h) + CUL4A-isoform2(h) <==> JAB1(h):CUL4A-isoform2(h) (binding)
JAB1(h) + DDB1(h):CUL4A-isoform2(h) <==> JAB1(h):DDB1(h):CUL4A-isoform2(h) (binding)
Bcl-3(h) + JAB1(h) <==> Bcl-3(h):JAB1(h) (binding)
Cops5(h) --> JAB1(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
2	N-acetylalanine.		Swiss-Prot 53.0

Transcription Factors [Top]