| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10458 |
Name | BAIAP2 |
Synonymous | BAI1-associated protein 2;BAIAP2;BAI1-associated protein 2 |
Definition | IRS-58|IRSp53/58|brain-specific angiogenesis inhibitor 1-associated protein 2|fas ligand-associated factor 3|insulin receptor substrate p53/p58|insulin receptor substrate protein of 53 kDa |
Position | 17q25 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | IRSp53(h) + WAVE-1(h) <==> IRSp53(h):WAVE-1(h) (binding) | IRSp53(h) + WAVE2(h) <==> IRSp53(h):WAVE2(h) (binding) | IRSp53(h) + WAVE-3(h) <==> IRSp53(h):WAVE-3(h) (binding) | WAVE-1(m.s.) + IRSp53(h) <==> WAVE-1(m.s.):IRSp53(h) (binding) | IRSp53(h) + IRSp53(h) <==> IRSp53(h):IRSp53(h) (binding) | IRSp53(h) + Espn(r) <==> IRSp53(h):Espn(r) (binding) | IRSp53(h) + BAI1(h) <==> IRSp53(h):BAI1(h) (binding) | SSTRIP(h) + IRSp53(h) <==> SSTRIP(h):IRSp53(h) (binding) | 14-3-3gamma(h) + IRSp53(h) <==> 14-3-3gamma(h):IRSp53(h) (binding) | Eps8(h) + IRSp53(h) <==> Eps8(h):IRSp53(h) (binding) | IRSp53(h) + SPIN90(h) <==> IRSp53(h):SPIN90(h) (binding) | Rac1(m.s.) + IRSp53(h) <==> Rac1(m.s.):IRSp53(h) (binding) | BAIAP2(h) --> IRSp53(h) (expression). | Rac1(m.s.) --> IRSp53(h) (activation) | Cdc42(m.s.) --> IRSp53(h) (activation) | BAIAP2(h) --> IRSp53-isoform5(h) (expression). | BAIAP2(h) --> IRSp53-isoform1(h) (expression). | BAIAP2(h) --> IRSp53-isoform2(h) (expression). | SSTRIP(h) + IRSp53-isoform4(h) <==> SSTRIP(h):IRSp53-isoform4(h) (binding) | GTP:G-gamma(h):Cdc42(h) + IRSp53-isoform4(h) <==> GTP:G-gamma(h):Cdc42(h):IRSp53-isoform4(h) (binding) | BAIAP2(h) --> IRSp53-isoform4(h) (expression). | BAIAP2(h) --> IRSp53-isoform6(h) (expression). | BAIAP2(h) --> IRSp53-isoform3(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 325 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 337 | Phosphotyrosine. | Swiss-Prot 53.0 | 452 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 453 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 454 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 491 | Phosphotyrosine. | Swiss-Prot 53.0 | 505 | Phosphotyrosine. | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr17 |
Promoter: 76622057 - 76624057 | GSE27584 |
chr17 |
Promoter: 76622057 - 76624057 | GSE27584 |
chr17 |
Promoter: 76622057 - 76624057 | GSE27584 |
chr17 |
Promoter: 76622057 - 76624057 | Agilent_014791_44K |