Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

10458

Name

BAIAP2

Synonymous

BAI1-associated protein 2;BAIAP2;BAI1-associated protein 2

Definition

IRS-58|IRSp53/58|brain-specific angiogenesis inhibitor 1-associated protein 2|fas ligand-associated factor 3|insulin receptor substrate p53/p58|insulin receptor substrate protein of 53 kDa

Position

17q25

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

IRSp53(h) + WAVE-1(h) <==> IRSp53(h):WAVE-1(h) (binding)
IRSp53(h) + WAVE2(h) <==> IRSp53(h):WAVE2(h) (binding)
IRSp53(h) + WAVE-3(h) <==> IRSp53(h):WAVE-3(h) (binding)
WAVE-1(m.s.) + IRSp53(h) <==> WAVE-1(m.s.):IRSp53(h) (binding)
IRSp53(h) + IRSp53(h) <==> IRSp53(h):IRSp53(h) (binding)
IRSp53(h) + Espn(r) <==> IRSp53(h):Espn(r) (binding)
IRSp53(h) + BAI1(h) <==> IRSp53(h):BAI1(h) (binding)
SSTRIP(h) + IRSp53(h) <==> SSTRIP(h):IRSp53(h) (binding)
14-3-3gamma(h) + IRSp53(h) <==> 14-3-3gamma(h):IRSp53(h) (binding)
Eps8(h) + IRSp53(h) <==> Eps8(h):IRSp53(h) (binding)
IRSp53(h) + SPIN90(h) <==> IRSp53(h):SPIN90(h) (binding)
Rac1(m.s.) + IRSp53(h) <==> Rac1(m.s.):IRSp53(h) (binding)
BAIAP2(h) --> IRSp53(h) (expression).
Rac1(m.s.) --> IRSp53(h) (activation)
Cdc42(m.s.) --> IRSp53(h) (activation)
BAIAP2(h) --> IRSp53-isoform5(h) (expression).
BAIAP2(h) --> IRSp53-isoform1(h) (expression).
BAIAP2(h) --> IRSp53-isoform2(h) (expression).
SSTRIP(h) + IRSp53-isoform4(h) <==> SSTRIP(h):IRSp53-isoform4(h) (binding)
GTP:G-gamma(h):Cdc42(h) + IRSp53-isoform4(h) <==> GTP:G-gamma(h):Cdc42(h):IRSp53-isoform4(h) (binding)
BAIAP2(h) --> IRSp53-isoform4(h) (expression).
BAIAP2(h) --> IRSp53-isoform6(h) (expression).
BAIAP2(h) --> IRSp53-isoform3(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

325Phosphoserine (By similarity).Swiss-Prot 53.0
337Phosphotyrosine.Swiss-Prot 53.0
452Phosphoserine (By similarity).Swiss-Prot 53.0
453Phosphoserine (By similarity).Swiss-Prot 53.0
454Phosphoserine (By similarity).Swiss-Prot 53.0
491Phosphotyrosine.Swiss-Prot 53.0
505Phosphotyrosine.Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr17

Promoter: 76622057 - 76624057GSE27584

chr17

Promoter: 76622057 - 76624057GSE27584

chr17

Promoter: 76622057 - 76624057GSE27584

chr17

Promoter: 76622057 - 76624057Agilent_014791_44K