Entrez Gene

Basic Information
Gene ID	10451
Name	VAV3
Synonymous	vav 3 guanine nucleotide exchange factor;VAV3;vav 3 guanine nucleotide exchange factor
Definition	VAV-3\|guanine nucleotide exchange factor VAV3\|vav 3 oncogene
Position	1p13.3
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
Vav-3(h) + ATP --> Vav-3(h){pY} + ADP (phosphorylation)
Rac1(m.s.) + Vav-3(h) <==> Rac1(m.s.):Vav-3(h) (binding)
RhoA(m.s.) + Vav-3(h) <==> RhoA(m.s.):Vav-3(h) (binding)
RhoG(m.s.) + Vav-3(h) <==> RhoG(m.s.):Vav-3(h) (binding)
RhoG(m.s.):GDP + Vav-3(h) <==> RhoG(m.s.):GDP:Vav-3(h) (binding)
Vav-3(h) + RhoG(m.s.):GTP <==> Vav-3(h):RhoG(m.s.):GTP (binding)
RhoA(m.s.):GDP + Vav-3(h) <==> RhoA(m.s.):GDP:Vav-3(h) (binding)
RhoA(m.s.):GTP + Vav-3(h) <==> RhoA(m.s.):GTP:Vav-3(h) (binding)
Vav-3(h) + ATP --Hck(m.s.)--> Vav-3(h){pY} + ADP (phosphorylation)
Vav-3(h) + c-Ros(h) <==> Vav-3(h):c-Ros(h) (binding)
ErbB1-p170(h){pY1016}{pY1172} + Vav-3(h) <==> ErbB1-p170(h){pY1016}{pY1172}:Vav-3(h) (binding)
ErbB2(h){pY1221} + Vav-3(h) <==> ErbB2(h){pY1221}:Vav-3(h) (binding)
ErbB3-isoform1(h){pY1276} + Vav-3(h) <==> ErbB3-isoform1(h){pY1276}:Vav-3(h) (binding)
ErbB4(h){pY1162} + Vav-3(h) <==> ErbB4(h){pY1162}:Vav-3(h) (binding)
Vav-3(h) + ATP --> Vav-3(h){pY173} + ADP (phosphorylation)
Vav-3(h) --> Vav-3(h) (translocation)
VAV3(h) --> Vav-3(h) (expression).
Vav-3(h) --> Vav-3(h) (translocation)
Rac1(m.s.):GDP + GTP --Vav-3(h)--> Rac1(m.s.):GTP + GDP (exchange)
RhoA(m.s.):GDP + GTP --Vav-3(h)--> RhoA(m.s.):GTP + GDP (exchange)
RhoG(m.s.):GDP + GTP --Vav-3(h)--> RhoG(m.s.):GTP + GDP (exchange)
VAV3(h) --> Vav-3-alpha(h) (expression).
VAV3(h) --> Vav-3-beta(h) (expression).

Post Translational Modification [Top]
	There is no record for VAV3

Transcription Factors [Top]